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G L Conn

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Articles 12
Citations 300
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Recent Articles
1.
Hobbs J, Munger S, Conn G
Acta Crystallogr Sect F Struct Biol Cryst Commun . 2007 Mar; 63(Pt 3):162-7. PMID: 17329805
The X-ray crystal structure of a single-chain monellin protein (MNEI) has been determined at 1.15 A resolution. The model was refined to convergence employing anisotropic displacement parameters and riding H...
2.
Conn G, Draper D, Lattman E, Gittis A
Science . 1999 May; 284(5417):1171-4. PMID: 10325228
The structure of a highly conserved complex between a 58-nucleotide domain of large subunit ribosomal RNA and the RNA-binding domain of ribosomal protein L11 has been solved at 2.8 angstrom...
3.
Conn G, Brown T, Leonard G
Nucleic Acids Res . 1998 Dec; 27(2):555-61. PMID: 9862980
The crystal structure of the RNA/DNA hybrid r(GAAGAGAAGC). d(GCTTCTCTTC) has been solved and refined at 2.5 A resolution. The refinement procedure converged at R = 0.181 for all reflections in...
4.
Conn G, Gutell R, Draper D
Biochemistry . 1998 Aug; 37(34):11980-8. PMID: 9718323
Comparative sequence analysis reveals a coordinated set of nucleotide exchanges between the base pair 1092/1099 and the unpaired position 1072 [(1092/1099)1072] in the L11 binding domain of 23S ribosomal RNA....
5.
Conn G, Draper D
Curr Opin Struct Biol . 1998 Jul; 8(3):278-85. PMID: 9666322
New information concerning RNA structure is accumulating at an ever increasing rate-from short helices with mismatched bases of 5S rRNA and complex RNA aptamers. The importance of recurring structural motifs,...
6.
Gyi J, Lane A, Conn G, Brown T
Nucleic Acids Res . 1998 Jun; 26(13):3104-10. PMID: 9628906
The stereochemical and dynamic properties of the C2' hydroxyl group in several DNA.RNA hybrids have been measured by NMR and compared with the homologous RNA duplex. The C2'-OH NMR signals...
7.
Gyi J, Lane A, Conn G, Brown T
Biochemistry . 1998 Feb; 37(1):73-80. PMID: 9425027
The structures of d(GAAGAGAAGC).d(GCTTCTCTTC), d(GAAGAGAAGC). r(GCUUCUCUUC), r(GAAGAGAAGC).d(GCTTCTCTTC), and r(GAAGAGAAGC). r(GCUUCUCUUC) have been determined in solution from NMR data. Globally, the pure DNA and RNA duplexes were in the B and...
8.
Bonifacio G, Brown T, Conn G, Lane A
Biophys J . 1997 Sep; 73(3):1532-8. PMID: 9284320
The electrophoretic behavior of defined DNA and RNA oligonucleotide duplexes from 10 to 20 bp in length has been investigated as a function of salt conditions, gel concentration, and temperature....
9.
Conte M, Conn G, Brown T, Lane A
Nucleic Acids Res . 1997 Jul; 25(13):2627-34. PMID: 9185574
The thermodynamic stability of nine dodecamers (four DNA and five RNA) of the same base composition has been compared by UV-melting. TheDeltaG of stabilisation were in the order: r(GACUGAUCAGUC)2>r(CGCAAATTTGCG)2 approximately...
10.
Sutton D, Conn G, Brown T, Lane A
Biochem J . 1997 Jan; 321 ( Pt 2):481-6. PMID: 9020884
We have developed a sensitive continuous assay for nucleases using proton release. The assay has been applied to the determination of the kinetics of DNase I acting on short, defined...