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G Jayandharan

Explore the profile of G Jayandharan including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 11
Citations 82
Followers 0
Related Specialties
Hematology
General Medicine
Pediatrics
Top 10 Co-Authors
M Chandy
A Srivastava
R V Shaji
S Baidya
S C Nair
A Viswabandya
M Spreafico
F Peyvandi
B George
Saly Usher
Published In
J Thromb Haemost
Haemophilia
Indian Pediatr
Natl Med J India
Affiliations
Soon will be listed here.
Recent Articles
1.
Mutations in the MCFD2 gene are predominant among patients with hereditary combined FV and FVIII deficiency (F5F8D) in India
Jayandharan G, Spreafico M, Viswabandya A, Chandy M, Srivastava A, Peyvandi F
Haemophilia . 2007 Jul; 13(4):413-9. PMID: 17610559
Combined FV and FVIII deficiency (F5F8D) is a rare (1:1.000.000) autosomal recessive disorder caused by a defect in the LMAN1 or MCFD2 genes, encoding for a FV and FVIII cargo...
2.
Molecular screening of the neutrophil elastase gene in congenital neutropenia
Thomas M, Jayandharan G, Chandy M
Indian Pediatr . 2007 Jan; 43(12):1081-4. PMID: 17202606
Congenital neutropenia is a rare hematopoietic disease, which occurs sporadically or as an auto-somal dominant inherited disorder. Pathogenesis of congenital neutropenia can now be attributed to mutations of the ELA2...
3.
A new multiplex PCR and conformation-sensitive gel electrophoresis strategy for mutation detection in the platelet glycoprotein alphaIIb and beta3 genes
Jayandharan G, Nelson E, Baidya S, Chandy M, Srivastava A
J Thromb Haemost . 2006 Nov; 5(1):206-9. PMID: 17083650
No abstract available.
4.
Genetic diagnosis of haemophilia and other inherited bleeding disorders
Peyvandi F, Jayandharan G, Chandy M, Srivastava A, Nakaya S, Johnson M, et al.
Haemophilia . 2006 May; 12 Suppl 3:82-9. PMID: 16684001
Inherited deficiencies of plasma proteins involved in blood coagulation generally lead to lifelong bleeding disorders, whose severity is inversely proportional to the degree of factor deficiency. Haemophilia A and B,...
5.
Identification of factor VIII gene mutations in 101 patients with haemophilia A: mutation analysis by inversion screening and multiplex PCR and CSGE and molecular modelling of 10 novel missense substitutions
Jayandharan G, Shaji R, Baidya S, Nair S, Chandy M, Srivastava A
Haemophilia . 2005 Sep; 11(5):481-91. PMID: 16128892
Haemophilia A (HA) is an X-linked bleeding disorder caused by diverse mutations in the human coagulation factor VIII (FVIII) gene. We have analysed DNA from 109 unrelated Indian patients with...
6.
Six novel mutations including triple heterozygosity for Phe31Ser, 514delT and 516T-->G factor X gene mutations are responsible for congenital factor X deficiency in patients of Nepali and Indian origin
Jayandharan G, Viswabandya A, Baidya S, Nair S, Shaji R, George B, et al.
J Thromb Haemost . 2005 May; 3(7):1482-7. PMID: 15892863
Factor X (FX) deficiency is a rare (1 : 100000) autosomal recessive disorder caused by heterogeneous mutations in FX gene. We have studied the molecular basis this disease in six...
7.
Molecular genetics of hereditary prothrombin deficiency in Indian patients: identification of a novel Ala362 --> Thr (Prothrombin Vellore 1) mutation
Jayandharan G, Viswabandya A, Baidya S, Nair S, Shaji R, Chandy M, et al.
J Thromb Haemost . 2005 May; 3(7):1446-53. PMID: 15892853
Prothrombin deficiency is a rare (1:200 000) autosomal recessive disorder caused by diverse mutations in prothrombin gene. We have studied the molecular basis of this disorder in four unrelated Indian...
8.
Novel missense mutations in two patients with factor XI deficiency (Val271Leu and Tyr351Ser) and one patient with combined factor XI and factor IX deficiency (Phe349Val)
Jayandharan G, Shaji R, Nair S, Chandy M, Srivastava A
J Thromb Haemost . 2005 Apr; 3(4):808-11. PMID: 15842381
No abstract available.
9.
Informativeness of linkage analysis for genetic diagnosis of haemophilia A in India
Jayandharan G, Shaji R, George B, Chandy M, Srivastava A
Haemophilia . 2004 Sep; 10(5):553-9. PMID: 15357783
The objective of this study was to assess the frequency of factor VIII (FVIII) gene intron 1 and intron 22 inversions and the informativeness of polymorphic markers for the genetic...
10.
Prenatal diagnosis of Glanzmann thrombasthenia
Srivastava A, Usher S, Nelson E, Jayandharan G, Shaji R, Chandy M, et al.
Natl Med J India . 2003 Nov; 16(4):207-8. PMID: 14606769
Background: Glanzmann thrombasthenia (GT) is an autosomal recessive disorder of platelet function, which results in major morbidity due to persistent, spontaneous, mucocutaneous bleeding and menorrhagia in women. Platelet transfusions are...