G J Poelarends
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Explore the profile of G J Poelarends including associated specialties, affiliations and a list of published articles.
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12
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248
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Recent Articles
1.
Poelarends G, Veetil V, Whitman C
Cell Mol Life Sci
. 2008 Aug;
65(22):3606-18.
PMID: 18695941
Tautomerase superfamily members have an amino-terminal proline and a beta-alpha-beta fold, and include 4-oxalocrotonate tautomerase (4-OT), 5-(carboxymethyl)-2-hydroxymuconate isomerase (CHMI), trans- and cis-3-chloroacrylic acid dehalogenase (CaaD and cis-CaaD, respectively), malonate semialdehyde...
2.
Mazurkiewicz P, Sakamoto K, Poelarends G, Konings W
Mini Rev Med Chem
. 2005 Feb;
5(2):173-81.
PMID: 15720287
Gram-positive lactic acid bacteria possess several Multi-Drug Resistance systems (MDRs) that excrete out of the cell a wide variety of mainly cationic lipophilic cytotoxic compounds as well as many clinically...
3.
van Hylckama Vlieg J, Tang L, Lutje Spelberg J, Smilda T, Poelarends G, Bosma T, et al.
J Bacteriol
. 2001 Aug;
183(17):5058-66.
PMID: 11489858
Halohydrin dehalogenases, also known as haloalcohol dehalogenases or halohydrin hydrogen-halide lyases, catalyze the nucleophilic displacement of a halogen by a vicinal hydroxyl function in halohydrins to yield epoxides. Three novel...
4.
Poelarends G, Saunier R, Janssen D
J Bacteriol
. 2001 Jun;
183(14):4269-77.
PMID: 11418568
The genes (caaD1 and caaD2) encoding the trans-3-chloroacrylic acid dehalogenase (CaaD) of the 1,3-dichloropropene-utilizing bacterium Pseudomonas pavonaceae 170 were cloned and heterologously expressed in Escherichia coli and Pseudomonas sp. strain...
5.
Janssen D, Oppentocht J, Poelarends G
Curr Opin Biotechnol
. 2001 Jun;
12(3):254-8.
PMID: 11404103
Novel dehalogenases have been identified recently in various bacteria that utilise halogenated substrates. X-ray studies and sequence analysis have revealed insight into the molecular mechanisms of hydrolytic dehalogenases. Furthermore, genetic...
6.
van Hylckama Vlieg J, Poelarends G, Mars A, Janssen D
Curr Opin Microbiol
. 2000 Jun;
3(3):257-62.
PMID: 10851165
The reactivity and toxicity of metabolic intermediates that are generated by initial biotransformation reactions can be a major limiting factor for biodegradation of halogenated organic compounds. Recent work on the...
7.
Poelarends G, Zandstra M, Bosma T, Kulakov L, Larkin M, Marchesi J, et al.
J Bacteriol
. 2000 Apr;
182(10):2725-31.
PMID: 10781539
The sequences of the 16S rRNA and haloalkane dehalogenase (dhaA) genes of five gram-positive haloalkane-utilizing bacteria isolated from contaminated sites in Europe, Japan, and the United States and of the...
8.
Poelarends G, Kulakov L, Larkin M, van Hylckama Vlieg J, Janssen D
J Bacteriol
. 2000 Mar;
182(8):2191-9.
PMID: 10735862
The haloalkane-degrading bacteria Rhodococcus rhodochrous NCIMB13064, Pseudomonas pavonaceae 170, and Mycobacterium sp. strain GP1 share a highly conserved haloalkane dehalogenase gene (dhaA). Here, we describe the extent of the conserved...
9.
Bosma T, Kruizinga E, de Bruin E, Poelarends G, Janssen D
Appl Environ Microbiol
. 1999 Oct;
65(10):4575-81.
PMID: 10508091
Trihalogenated propanes are toxic and recalcitrant organic compounds. Attempts to obtain pure bacterial cultures able to use these compounds as sole carbon and energy sources were unsuccessful. Both the haloalkane...
10.
Poelarends G, van Hylckama Vlieg J, Marchesi J, Freitas dos Santos L, Janssen D
J Bacteriol
. 1999 Mar;
181(7):2050-8.
PMID: 10094681
The newly isolated bacterial strain GP1 can utilize 1, 2-dibromoethane as the sole carbon and energy source. On the basis of 16S rRNA gene sequence analysis, the organism was identified...