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G E Schulz

Explore the profile of G E Schulz including associated specialties, affiliations and a list of published articles. Areas
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Articles 151
Citations 3836
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Recent Articles
1.
Kloer D, Schulz G
Cell Mol Life Sci . 2006 Aug; 63(19-20):2291-303. PMID: 16909205
Apo-carotenoid compounds such as retinol (vitamin A) are involved in a variety of cellular processes and are found in all kingdoms of life. Instead of being synthesized from small precursors,...
2.
Ikeda K, Schiltz E, Fujii T, Takahashi M, Mitsui K, Kodera Y, et al.
Amino Acids . 2005 Jun; 29(3):283-7. PMID: 15977040
Phenylketonuria (PKU) is an autosomal recessive genetic disease caused by the defects in the phenylalanine hydroxylase (PAH) gene. Individuals homozygous for defective PAH alleles show elevated levels of systemic phenylalanine...
3.
Jelakovic S, Schulz G
J Mol Biol . 2001 Sep; 312(1):143-55. PMID: 11545592
The enzyme CMP-Kdo synthetase (CKS) catalyzes the activation of the sugar Kdo (2-keto-3-deoxy-manno-octonic acid) by forming a monophosphate diester. CKS is a pharmaceutical target because CMP-Kdo is used in the...
4.
Wurth C, Kessler U, Vogt J, Schulz G, Folkers G, Scapozza L
Protein Sci . 2001 Mar; 10(1):63-73. PMID: 11266595
The structure of Herpes simplex virus type 1 thymidine kinase (TK(HSV1)) is known at high resolution in complex with a series of ligands and exhibits important structural similarities to the...
5.
Vogt J, Perozzo R, Pautsch A, Prota A, Schelling P, Pilger B, et al.
Proteins . 2000 Oct; 41(4):545-53. PMID: 11056041
The crystal structures of the full-length Herpes simplex virus type 1 thymidine kinase in its unligated form and in a complex with an adenine analogue have been determined at 1.9...
6.
Joerger A, Schulz G
J Mol Biol . 2000 Oct; 303(4):531-43. PMID: 11054289
The crystal structures of l-fuculose-1-phosphate aldolase (FucA) with and without a ligated analogue of dihydroxyacetone phosphate (DHAP) and of a number of active center mutants have resulted in a model...
7.
Brix J, Ziegler G, Dietmeier K, Schneider-Mergener J, Schulz G, Pfanner N
J Mol Biol . 2000 Oct; 303(4):479-88. PMID: 11054285
The mitochondrial import receptor of 70 kDa, Tom70, preferentially recognizes precursors of membrane proteins with internal targeting signals. We report the identification of a stably folded 25 kDa core domain...
8.
Ziegler G, Schulz G
Biochemistry . 2000 Sep; 39(36):10986-95. PMID: 10998235
Adrenodoxin reductase is a flavoenzyme that shuffles electrons for the biosynthesis of steroids. Its chain topology belongs to the glutathione reductase family of disulfide oxidoreductases, all of which bind FAD...
9.
Schulz G
Curr Opin Struct Biol . 2000 Sep; 10(4):443-7. PMID: 10981633
beta-Barrel proteins are found in the outer membranes of bacteria, mitochondria and chloroplasts. The presently known sizes range from small eight-stranded to large twenty-two-stranded beta barrels existing as monomers and...
10.
Prota A, Vogt J, Pilger B, Perozzo R, Wurth C, Marquez V, et al.
Biochemistry . 2000 Aug; 39(31):9597-603. PMID: 10924157
Kinetic and crystallographic analyses of wild-type Herpes simplex virus type 1 thymidine kinase (TK(HSV1)) and its Y101F-mutant [TK(HSV1)(Y101F)] acting on the potent antiviral drug 2'-exo-methanocarba-thymidine (MCT) have been performed. The...