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G Cosemans

Explore the profile of G Cosemans including associated specialties, affiliations and a list of published articles. Areas
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Articles 4
Citations 26
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Recent Articles
1.
Bekaert B, Boel A, Rybouchkin A, Cosemans G, Declercq S, Chuva de Sousa Lopes S, et al.
J Assist Reprod Genet . 2024 Apr; 41(6):1605-1617. PMID: 38557805
Purpose: Unpredictable genetic modifications and chromosomal aberrations following CRISPR/Cas9 administration hamper the efficacy of germline editing. Repair events triggered by double-strand DNA breaks (DSBs) besides non-homologous end joining and repair...
2.
Stamatiadis P, Cosemans G, Boel A, Menten B, De Sutter P, Stoop D, et al.
Hum Reprod . 2022 Jun; 37(8):1760-1773. PMID: 35700449
Study Question: What is the role of transcriptional-enhanced associate (TEA) domain family member 4 (TEAD4) in trophectoderm (TE) differentiation during human embryo preimplantation development in comparison to mouse? Summary Answer:...
3.
Bekaert B, Boel A, Cosemans G, De Witte L, Menten B, Heindryckx B
Semin Cell Dev Biol . 2022 Mar; 131:93-107. PMID: 35305903
The ease and efficacy of CRISPR/Cas9 germline gene editing in animal models paved the way to human germline gene editing (HGGE), by which permanent changes can be introduced into the...
4.
Stamatiadis P, Boel A, Cosemans G, Popovic M, Bekaert B, Guggilla R, et al.
Hum Reprod . 2021 Feb; 36(5):1242-1252. PMID: 33609360
Study Question: What is the role of POU class 5 homeobox 1 (POU5F1) in human preimplantation development and how does it compare with the mouse model? Summary Answer: POU5F1 is...