G C Goeringer
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Explore the profile of G C Goeringer including associated specialties, affiliations and a list of published articles.
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20
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43
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Recent Articles
1.
DeSesso J, Jacobson C, Scialli A, Goeringer G
Teratology
. 2000 Oct;
62(5):346-55.
PMID: 11029153
Background: Cellular debris, an indicator of cell death, appears in limb buds of gestational day 12 rabbit embryos 4 hr after either a subcutaneous injection of hydroxyurea to pregnant rabbits...
2.
Scialli A, Waterhouse T, DeSesso J, Rahman A, Goeringer G
Teratology
. 1998 Feb;
56(5):305-10.
PMID: 9451754
Paclitaxel is an anticancer drug that has demonstrated severe embryotoxicity in chicks. This embryotoxicity is reduced by liposome encapsulation of the drug. The current study was designed to evaluate the...
3.
Scialli A, DeSesso J, Rahman A, Husain S, Goeringer G
Pharmacology
. 1995 Sep;
51(3):145-51.
PMID: 7501699
Taxol, an inhibitor of microtubule disaggregation, is used in the therapy of breast, ovarian, and other human malignancies. The toxicity of taxol administration is due in part to the polyoxyethylated...
4.
DeSesso J, Scialli A, Goeringer G
Teratology
. 1994 Apr;
49(4):248-59.
PMID: 8073363
Hydroxyurea (HU) is a potent mammalian teratogen. Within 2-4 hours after maternal injection, HU causes 1) a rapid episode of embryonic cell death and 2) profound inhibition of embryonic DNA...
5.
Scialli A, DeSesso J, Goeringer G
Teratog Carcinog Mutagen
. 1994 Jan;
14(1):23-30.
PMID: 7514314
Taxol, an inhibitor of microtubule disassembly, is currently under investigation in the therapy of several human cancers. The current investigation was undertaken to characterize potential taxol developmental toxicity in chicks....
6.
DeSesso J, Goeringer G
Teratology
. 1992 Mar;
45(3):271-83.
PMID: 1631781
Dihydrofolate reductase reduces folic acid to tetrahydrofolate as a prerequisite to one-carbon metabolism, which is required for normal embryonic de novo DNA synthesis. The developmental toxicity of methotrexate (MTX) has...
7.
DeSesso J, Goeringer G
Teratology
. 1991 Mar;
43(3):201-15.
PMID: 2014483
Methotrexate (MTX) is lethal or teratogenic to embryos of all species tested. New Zealand white rabbit embryos are relatively resistant to the embryolethal effects of MTX. However, when pregnant does...
8.
Scialli A, Goeringer G
In Vitro Cell Dev Biol
. 1990 May;
26(5):507-10.
PMID: 2351643
In an attempt to prolong the survival of the explanted early chick embryo heart, hearts at stages 10 to 28 were cultured in supplemented Dulbecco's modified Eagle's medium with or...
9.
DeSesso J, Goeringer G
Toxicol Ind Health
. 1990 Jan;
6(1):109-21.
PMID: 2349571
Hydroxylamine (HA) is an important reducing agent that is used in several industries. HA is a moderate irritant and a powerful inducer of methemoglobinemia. HA has been shown to react...
10.
DeSesso J, Goeringer G
Reprod Toxicol
. 1990 Jan;
4(4):267-75.
PMID: 2136047
Hydroxyurea (HU) is a potent teratogen that causes a characteristic, rapidly occurring episode of embryonic cell death 2 to 4 h after subcutaneously injecting 650 mg/kg of HU into pregnant...