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G Brett Moreau

Explore the profile of G Brett Moreau including associated specialties, affiliations and a list of published articles. Areas
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Articles 17
Citations 212
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Recent Articles
1.
Naz F, Hagspiel N, Xu F, Thompson B, Moreau G, Young M, et al.
NPJ Vaccines . 2025 Feb; 10(1):33. PMID: 39966390
We report a comprehensive evaluation of the toxin B (TcdB) vaccine adjuvanted with a dual Toll-like receptor ligand liposome adjuvant for Clostridioides difficile infection (CDI). The vaccine completely protected mice...
2.
Jamil Z, Hanson G, Iqbal J, Moreau G, Iqbal N, Ahmed S, et al.
medRxiv . 2024 Dec; PMID: 39711734
Ready-to-use supplemental foods (RUSF) are energy-dense meals formulated to prevent and treat moderate and severe childhood acute malnutrition (MAM and SAM) in high-risk settings. Although lifesaving, the degree and durability...
3.
Naz F, Hagspiel N, Xu F, Thompson B, Moreau G, Young M, et al.
bioRxiv . 2024 Dec; PMID: 39651154
We report a comprehensive evaluation of the toxin B (TcdB) vaccine adjuvanted with a dual Toll-like receptor ligand liposome adjuvant for infection (CDI). The vaccine completely protected mice from a...
4.
Moreau G, Young M, Behm B, Tanyuksel M, Ramakrishnan G, Petri Jr W
medRxiv . 2024 Dec; PMID: 39649613
Recurrent infection (CDI) is a major health threat with significant mortality and financial costs. Fecal Microbiota Transplantation (FMT) is an effective therapy, however the mechanisms by which it acts, particularly...
5.
Rivet-Noor C, Merchak A, Render C, Gay N, Beiter R, Brown R, et al.
Brain Behav Immun . 2024 Apr; 119:665-680. PMID: 38579936
Depression is a prevalent psychological condition with limited treatment options. While its etiology is multifactorial, both chronic stress and changes in microbiome composition are associated with disease pathology. Stress is...
6.
Moreau G, Naz F, Petri Jr W
Anaerobe . 2024 Mar; 86:102841. PMID: 38521227
Objectives: Clostridioides difficile infection (CDI) is the leading hospital-acquired infection in North America. While previous work on fecal microbiota transplantation (FMT), a highly effective treatment for CDI, has focused on...
7.
Petri W, Hossain B, Kabir M, So H, Moreau G, Nayak U, et al.
medRxiv . 2023 Jul; PMID: 37425942
Background: is one of the top causes of diarrhea in Bangladesh infants. infections lead to the production of antibody immune responses, which were associated with a decrease in parasite burden...
8.
Sasson J, Moreau G, Petri Jr W
Ann Allergy Asthma Immunol . 2023 Mar; 130(6):727-732. PMID: 36924937
Although much has been learned about severe acute respiratory syndrome coronavirus 2 since December 2019, uneven global vaccine distribution, rapid viral spread, and variant evasion of preventative measures have led...
9.
Abhyankar M, Mann B, Sturek J, Brovero S, Moreau G, Sengar A, et al.
NPJ Vaccines . 2021 Nov; 6(1):137. PMID: 34795290
We developed a SARS-CoV-2 spike subunit vaccine formulation containing dual TLR ligand liposome adjuvant. The vaccine-induced robust systemic neutralizing antibodies and completely protected mice from a lethal challenge. Two immunizations...
10.
Donlan A, Sutherland T, Marie C, Preissner S, Bradley B, Carpenter R, et al.
JCI Insight . 2021 Jun; 6(15). PMID: 34185704
Immune dysregulation is characteristic of the more severe stages of SARS-CoV-2 infection. Understanding the mechanisms by which the immune system contributes to COVID-19 severity may open new avenues to treatment....