G A Patterson
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Explore the profile of G A Patterson including associated specialties, affiliations and a list of published articles.
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282
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2722
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Recent Articles
11.
Sugimoto S, Lin X, Lai J, Okazaki M, Das N, Li W, et al.
J Thorac Cardiovasc Surg
. 2009 Aug;
138(3):752-9.
PMID: 19698866
Objective: Endothelial cells express the ectoenzyme ectonucleoside adenosine triphosphate diphosphohydrolase, an apyrase that inhibits vascular inflammation by catalyzing the hydrolysis of adenosine triphosphate and adenosine diphosphate. However, ectonucleoside adenosine triphosphate...
12.
Sugimoto S, Lin X, Okazaki M, Lai J, Tietjens J, Huang H, et al.
Transplant Proc
. 2009 Mar;
41(1):388-90.
PMID: 19249563
In lung grafts, ischemia-reperfusion signals rapidly induce the recruitment and differentiation of host monocytes into macrophages and dendritic cells. The nature of ischemia-reperfusion signals are antigen independent, but have been...
13.
Okazaki M, Sugimoto S, Lai J, Kornfeld C, Hotchkiss R, Richardson S, et al.
Transplant Proc
. 2009 Mar;
41(1):385-7.
PMID: 19249562
Lung allografts are considered to be more immunogenic than other solid organs. Little is known about the effectiveness of immunosuppressive regimens after lung transplantation. Herein, we describe a novel model...
14.
Huang H, Yusen R, Meyers B, Walter M, Mohanakumar T, Patterson G, et al.
Am J Transplant
. 2008 Sep;
8(11):2454-62.
PMID: 18785961
Primary graft dysfunction (PGD) is a common early complication after lung transplantation. We conducted a retrospective cohort study of 334 recipients to evaluate the impact of PGD graded at 24,...
15.
Ray M, Dharmarajan S, Freudenberg J, Zhang W, Patterson G
Am J Transplant
. 2007 Sep;
7(10):2396-405.
PMID: 17845573
Lung transplantation is the treatment of choice for end-stage pulmonary diseases. A limited donor supply has resulted in 4,000 patients on the waiting list. Currently, 10-20% of donor organs offered...
16.
Okazaki M, Krupnick A, Kornfeld C, Lai J, Ritter J, Richardson S, et al.
Am J Transplant
. 2007 May;
7(6):1672-9.
PMID: 17511692
Outcomes after lung transplantation are markedly inferior to those after other solid organ transplants. A better understanding of cellular and molecular mechanisms contributing to lung graft injury will be critical...
17.
Okazaki M, Kreisel F, Richardson S, Kreisel D, Krupnick A, Patterson G, et al.
Am J Transplant
. 2007 Mar;
7(4):751-8.
PMID: 17391120
Ischemia reperfusion (I/R) injury following lung transplantation is exacerbated by the destruction of the endothelial cell barrier leading to pulmonary edema and dysregulated activated lymphocyte migration. Sphingosine 1-phosphate (S1P), a...
18.
Bharat A, Fields R, Steward N, Trulock E, Patterson G, Mohanakumar T
Am J Transplant
. 2006 Aug;
6(8):1799-808.
PMID: 16889540
Chronic human lung allograft rejection is manifested by bronchiolitis obliterans syndrome (BOS). BOS has a multifactorial etiology. Previous studies have indicated that both cellular and humoral alloimmunity play a significant...
19.
Keshavjee S, Davis R, Zamora M, de Perrot M, Patterson G
J Thorac Cardiovasc Surg
. 2005 Jan;
129(2):423-8.
PMID: 15678055
Objective: Complement activation has been shown to play a significant role in ischemia-reperfusion injury after lung transplantation. TP-10 (soluble complement receptor 1 inhibitor) inhibits the activation of complement by inactivating...
20.
Jaramillo A, Fernandez F, Kuo E, Trulock E, Patterson G, Mohanakumar T
Pediatr Transplant
. 2005 Jan;
9(1):84-93.
PMID: 15667618
Lung transplantation is recognized as the only viable treatment option in a variety of end-stage pulmonary diseases. However, the long-term survival after lung transplantation is limited by the development of...