Fumito Aranami
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Explore the profile of Fumito Aranami including associated specialties, affiliations and a list of published articles.
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12
Citations
306
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Recent Articles
1.
Furutani J, Segawa H, Aranami F, Kuwahara S, Sugano M, Bannai K, et al.
J Ren Nutr
. 2012 Jun;
23(2):e11-20.
PMID: 22677630
Background: Both organic and inorganic phosphorus (Pi) are present in regularly consumed foods, such as meats, eggs, and dairy products. Pi is often included in foods as an additive (as...
2.
Kuwahara S, Aranami F, Segawa H, Onitsuka A, Honda N, Tominaga R, et al.
J Med Invest
. 2012 Mar;
59(1-2):116-26.
PMID: 22450000
Mutations in the SLC34A3 gene, a sodium-dependent inorganic phosphate (Pi) cotransporter, also referred to as NaPi IIc, causes hereditary hypophosphatemic rickets with hypercalciuria (HHRH), an autosomal recessive disorder. In human...
3.
Haito-Sugino S, Ito M, Ohi A, Shiozaki Y, Kangawa N, Nishiyama T, et al.
Am J Physiol Cell Physiol
. 2011 Dec;
302(9):C1316-30.
PMID: 22159077
Mutations in the apically located Na(+)-dependent phosphate (NaPi) cotransporter, SLC34A3 (NaPi-IIc), are a cause of hereditary hypophosphatemic rickets with hypercalciuria (HHRH). We have characterized the impact of several HHRH mutations...
4.
Ohi A, Hanabusa E, Ueda O, Segawa H, Horiba N, Kaneko I, et al.
Am J Physiol Renal Physiol
. 2011 Aug;
301(5):F1105-13.
PMID: 21816756
An inorganic phosphate (P(i))-restricted diet is important for patients with chronic kidney disease and patients on hemodialysis. Phosphate binders are essential for preventing hyperphosphatemia and ectopic calcification. The sodium-dependent P(i)...
5.
Kaneko I, Segawa H, Furutani J, Kuwahara S, Aranami F, Hanabusa E, et al.
Pflugers Arch
. 2010 Nov;
461(1):77-90.
PMID: 21057807
We analyzed vitamin D receptor (VDR) (-/-) mice fed either a normal diet or a rescue diet. Weanling VDR (-/-) mice had hypophosphatemia and hyperphosphaturia. Renal Na(+)-dependent inorganic phosphate (Pi)...
6.
Tomoe Y, Segawa H, Shiozawa K, Kaneko I, Tominaga R, Hanabusa E, et al.
Am J Physiol Renal Physiol
. 2010 Apr;
298(6):F1341-50.
PMID: 20357029
In the present study, we evaluated the roles of type II and type III sodium-dependent P(i) cotransporters in fibroblast growth factor 23 (FGF23) activity by administering a vector encoding FGF23...
7.
Aranami F, Segawa H, Furutani J, Kuwahara S, Tominaga R, Hanabusa E, et al.
J Med Invest
. 2010 Mar;
57(1-2):95-108.
PMID: 20299748
Phosphaturia has been documented following cadmium (Cd) exposure in both humans and experimental animals. The fibroblast growth factor 23 (FGF23)/klotho axis serves as an essential phosphate homeostasis pathway in the...
8.
Segawa H, Onitsuka A, Furutani J, Kaneko I, Aranami F, Matsumoto N, et al.
Am J Physiol Renal Physiol
. 2009 Jul;
297(3):F671-8.
PMID: 19570882
Hereditary hypophosphatemic rickets with hypercalciuria (HHRH) is a rare autosomal recessively inherited disorder, characterized by hypophosphatemia, short stature, rickets and/or osteomalacia, and secondary absorptive hypercalciuria. HHRH is caused by a...
9.
Segawa H, Aranami F, Kaneko I, Tomoe Y, Miyamoto K
Bone
. 2009 Feb;
45 Suppl 1:S2-7.
PMID: 19232403
The renal type II Na/Pi cotransporters, Na/Pi-IIa and Na/Pi-IIc, are expressed in the brush border membrane (BBM) of the renal proximal tubule cells. Because it has long been thought that...
10.
Segawa H, Onitsuka A, Kuwahata M, Hanabusa E, Furutani J, Kaneko I, et al.
J Am Soc Nephrol
. 2008 Dec;
20(1):104-13.
PMID: 19056871
Primary renal inorganic phosphate (Pi) wasting leads to hypophosphatemia, which is associated with skeletal mineralization defects. In humans, mutations in the gene encoding the type IIc sodium-dependent phosphate transporter lead...