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Fumihiko Yasuno

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Articles 106
Citations 1926
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Recent Articles
1.
Ogata A, Ikenuma H, Yasuno F, Nihashi T, Hattori S, Sato Y, et al.
J Nucl Med . 2025 Jan; 66(2):302-308. PMID: 39746757
Microglia, the immune cells in the brain, play a significant role in the pathophysiology of neurodegenerative diseases. To visualize these cells in the living brain, we developed a PET ligand,...
2.
Yasuno F, Kimura Y, Ogata A, Ikenuma H, Abe J, Minami H, et al.
Brain Behav Immun Health . 2024 May; 38:100795. PMID: 38799793
Background: Positron emission tomography, which assesses the binding of translocator protein radiotracers, C-DPA-713, may be a sensitive method for determining glial-mediated neuroinflammation levels. This study investigated the relationship between regional...
3.
Saito S, Suzuki K, Ohtani R, Maki T, Kowa H, Tachibana H, et al.
JAMA Netw Open . 2023 Dec; 6(12):e2344938. PMID: 38048134
Importance: Recent evidence indicates the efficacy of β-amyloid immunotherapy for the treatment of Alzheimer disease, highlighting the need to promote β-amyloid removal from the brain. Cilostazol, a selective type 3...
4.
Yasuno F, Kimura Y, Ogata A, Ikenuma H, Abe J, Minami H, et al.
Brain Behav Immun . 2023 Aug; 114:214-220. PMID: 37648003
Background: Glial activation is central to the pathogenesis of Alzheimer's disease (AD). However, researchers have not demonstrated its relationship to longitudinal cognitive deterioration. We aimed to compare the prognostic effects...
5.
Kitamura S, Matsuoka K, Takahashi M, Hiroaki Y, Ishida R, Kishimoto N, et al.
J Psychiatr Res . 2023 Mar; 161:316-323. PMID: 36996724
Sensory over-responsivity (SOR) causes social and daily distress in individuals with autism spectrum disorder (ASD). Compared to typically developed (TD) individuals, ASD individuals are at higher risk of adverse childhood...
6.
Takeuchi M, Matsunaga M, Egashira R, Miyake A, Yasuno F, Nakano M, et al.
Front Psychiatry . 2022 Dec; 13:969833. PMID: 36532195
Introduction: Maternal depression is one of the important problems of postpartum women. For its early detection and appropriate treatment, it is necessary to identify women at high risk for depression...
7.
Yasuno F, Kimura Y, Ogata A, Ikenuma H, Abe J, Minami H, et al.
Psychogeriatrics . 2022 Nov; 23(1):126-135. PMID: 36403981
Background: The evaluation of C-DPA-713 binding using positron emission tomography for quantifying the translocator protein can be a sensitive approach in determining the level of glial activation induced by neuroinflammation....
8.
Yasuno F, Watanabe A, Kimura Y, Yamauchi Y, Ogata A, Ikenuma H, et al.
Brain Behav Immun Health . 2022 Nov; 26:100549. PMID: 36388135
Background: Neuroinflammation is a well-known feature of Alzheimer's disease (AD), and a blood-based test for estimating the levels of neuroinflammation would be expected. In this study, we examined and validated...
9.
Yasuno F, Minami H
Psychogeriatrics . 2022 Apr; 22(4):445-452. PMID: 35474398
Background: This study used positron emission tomography to examine whether the seasonal birth effect as an exogenic indicator of early life environmental factors influenced vulnerability to Alzheimer's disease (AD) pathology...
10.
Yasuno F, Kimura Y, Ogata A, Ikenuma H, Abe J, Minami H, et al.
Nucl Med Biol . 2022 Mar; 108-109:76-84. PMID: 35349913
Introduction: C-DPA-713 is a positron emission tomography (PET) radiotracer developed for imaging the expression of the translocator protein (TSPO) in glial cells, which is considered to be a marker of...