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Fumiaki Ayabe

Explore the profile of Fumiaki Ayabe including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 7
Citations 187
Followers 0
Related Specialties
Biology
Biochemistry
Cell Biology
Top 10 Co-Authors
Motonobu Katoh
Mitsuo Oshimura
Hiroshi Asahara
Yoshiaki Ito
Martin K Lotz
Akihiko Hasegawa
Toshiaki Inoue
Naoko Onizuka
Tetsuya Matsukawa
Hiroyuki Nakahara
Published In
Biochem Biophys Res Commun
Biomed Chromatogr
Nat Commun
Stem Cells
Arthritis Rheum
Affiliations
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Recent Articles
1.
Both microRNA-455-5p and -3p repress hypoxia-inducible factor-2α expression and coordinately regulate cartilage homeostasis
Ito Y, Matsuzaki T, Ayabe F, Mokuda S, Kurimoto R, Matsushima T, et al.
Nat Commun . 2021 Jul; 12(1):4148. PMID: 34230481
Osteoarthritis (OA), the most common aging-related joint disease, is caused by an imbalance between extracellular matrix synthesis and degradation. Here, we discover that both strands of microRNA-455 (miR-455), -5p and...
2.
Transcription factor Mohawk controls tenogenic differentiation of bone marrow mesenchymal stem cells in vitro and in vivo
Otabe K, Nakahara H, Hasegawa A, Matsukawa T, Ayabe F, Onizuka N, et al.
J Orthop Res . 2014 Oct; 33(1):1-8. PMID: 25312837
Mohawk homeobox (MKX) has been demonstrated as a tendon/ligament specific transcription factor. The aim of this study was to investigate the role of MKX in ligament/tenogenic differentiation of bone marrow...
3.
Transcription factor Mohawk and the pathogenesis of human anterior cruciate ligament degradation
Nakahara H, Hasegawa A, Otabe K, Ayabe F, Matsukawa T, Onizuka N, et al.
Arthritis Rheum . 2013 May; 65(8):2081-9. PMID: 23686683
Objective: To investigate the expression and function of Mohawk (MKX) in human adult anterior cruciate ligament (ACL) tissue and ligament cells from normal and osteoarthritis (OA)-affected knees. Methods: Knee joints...
4.
High-performance affinity chromatography method for identification of L-arginine interacting factors using magnetic nanobeads
Hiramoto M, Maekawa N, Kuge T, Ayabe F, Watanabe A, Masaike Y, et al.
Biomed Chromatogr . 2009 Oct; 24(6):606-12. PMID: 19810004
L-Arginine exhibits a wide range of biological activities through a complex and highly regulated set of pathways that remain incompletely understood at both the whole-body and the cellular levels. The...
5.
A novel expression system for genomic DNA loci using a human artificial chromosome vector with transformation-associated recombination cloning
Ayabe F, Katoh M, Inoue T, Kouprina N, Larionov V, Oshimura M
J Hum Genet . 2005 Oct; 50(11):592-599. PMID: 16231070
Following the recent completion of the human genome sequence, genomics research has shifted its focus to understanding gene complexity, expression, and regulation. However, in order to investigate such issues, there...
6.
A novel human artificial chromosome vector provides effective cell lineage-specific transgene expression in human mesenchymal stem cells
Ren X, Katoh M, Hoshiya H, Kurimasa A, Inoue T, Ayabe F, et al.
Stem Cells . 2005 Sep; 23(10):1608-16. PMID: 16141362
Mesenchymal stem cells (MSCs) hold promise for use in adult stem cell-mediated gene therapy. One of the major aims of stem cell-mediated gene therapy is to develop vectors that will...
7.
Construction of a novel human artificial chromosome vector for gene delivery
Katoh M, Ayabe F, Norikane S, Okada T, Masumoto H, Horike S, et al.
Biochem Biophys Res Commun . 2004 Sep; 321(2):280-90. PMID: 15358173
Potential problems of conventional transgenes include insertional disruption of the host genome and unpredictable, irreproducible expression of the transgene by random integration. Alternatively, human artificial chromosomes (HACs) can circumvent some...