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Fulu Liu

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Articles 22
Citations 2053
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Recent Articles
1.
Xing Z, Liu F, Feng J, Yu L, Wu Z, Zhao B, et al.
Nature . 2024 Nov; 637(8048):1118-1123. PMID: 39571610
Multicomponent reactions-those where three or more substrates combine into a product-have been highly useful in rapidly building chemical building blocks of increased complexity, but achieving this enzymatically has remained rare....
2.
Xu X, Liu F, Qiao W, Dong Y, Yang H, Liu F, et al.
Microorganisms . 2024 Apr; 12(4). PMID: 38674718
In lactic acid bacteria, the global transcriptional regulator CcpA regulates carbon metabolism by repressing and activating the central carbon metabolism pathway, thus decreasing or increasing the yield of certain metabolites...
3.
Qiao W, Liu F, Wan X, Qiao Y, Li R, Wu Z, et al.
Microorganisms . 2022 Jan; 10(1). PMID: 35056496
is a commonly used fermenting bacteria in cheese, beverages and meat products. Due to the lack of simplified chassis strains, it has not been widely used in the fields of...
4.
Wang X, Liu F, Zhang Y, Zhu D, Saris P, Xu H, et al.
Int J Biol Macromol . 2021 Jan; 173:399-408. PMID: 33454334
Herein, a new method was demonstrated for effective immobilization of the antibacterial peptide nisin on Grifola frondosa hydrophobin (HGFI), without the need of any additional complex reaction. Hydrophobin can self-assemble...
5.
Qiao W, Qiao Y, Liu F, Zhang Y, Li R, Wu Z, et al.
Microb Cell Fact . 2020 Dec; 19(1):225. PMID: 33298073
Background: In bioengineering, growth of microorganisms is limited because of environmental and industrial stresses during fermentation. This study aimed to construct a nisin-producing chassis Lactococcus lactis strain with genome-streamlined, low...
6.
Liu F, Zhang Y, Qiao W, Zhu D, Xu H, Saris P, et al.
Microb Cell Fact . 2019 Nov; 18(1):198. PMID: 31727072
Background: After 2.83% genome reduction in Lactococcus lactis NZ9000, a good candidate host for proteins production was obtained in our previous work. However, the gene deletion process was time consuming...
7.
Fu Y, Mu D, Qiao W, Zhu D, Wang X, Liu F, et al.
Front Microbiol . 2018 Apr; 9:547. PMID: 29628920
Nisin, an important bacteriocin from subsp., is primarily active against various Gram-positive bacteria. Leucocin C, produced by 4010, is a class IIa bacteriocin used to inhibit the growth of Because...
8.
Zhu D, Fu Y, Liu F, Xu H, Saris P, Qiao M
Microb Cell Fact . 2017 Jan; 16(1):1. PMID: 28049473
Background: The implementation of novel chassis organisms to be used as microbial cell factories in industrial applications is an intensive research field. Lactococcus lactis, which is one of the most...
9.
Zhu D, Liu F, Xu H, Bai Y, Zhang X, Saris P, et al.
FEMS Microbiol Lett . 2015 Jul; 362(16). PMID: 26156144
The synthesis of heterologous proteins in Lactococcus lactis is strongly influenced by the promoter selected for the expression. The nisin A promoter is commonly used for induced expression of proteins...
10.
Welch J, Ley T, Link D, Miller C, Larson D, Koboldt D, et al.
Cell . 2012 Jul; 150(2):264-78. PMID: 22817890
Most mutations in cancer genomes are thought to be acquired after the initiating event, which may cause genomic instability and drive clonal evolution. However, for acute myeloid leukemia (AML), normal...