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Fukui Shen

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Articles 21
Citations 71
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Recent Articles
1.
Liu K, Cheng C, Yan J, Chi F, Wang W, Shen F, et al.
Phytomedicine . 2025 Jan; 138:156392. PMID: 39826283
Background: Platelet adhesion to collagen, a critical initial step in thrombus formation, remains an underexplored therapeutic target in thrombosis. Current disease treatment strategies primarily focus on platelet activation and aggregation,...
2.
Zhang K, Luan G, Liu W, Shen F, Jiang M, Bai G
J Ethnopharmacol . 2024 Nov; 338(Pt 1):119018. PMID: 39489358
Ethnopharmacological Relevance: Angelica sinensis (Oliv.) Diels (AS), a medicinal plant renowned for its constipation-relieving properties, lacks comprehensive studies on its active pharmaceutical ingredients (APIs) and underlying mechanisms. In the gastrointestinal...
3.
Zhang K, Liu W, Shen F, Luan G, Han Y, Xu J, et al.
J Ethnopharmacol . 2024 Apr; 330:118217. PMID: 38641072
Ethnopharmacological Relevance: The natural anodyne Ligustilide (Lig), derived from Angelica sinensis (Oliv.) Diels and Ligusticum chuanxiong Hort., has been traditionally employed for its analgesic properties in the treatment of dysmenorrhea...
4.
Chu S, Shen F, Liu W, Zhang J, Wang X, Jiang M, et al.
Phytomedicine . 2024 Feb; 126:155200. PMID: 38387273
Background: The renin-angiotensin-aldosterone system (RAAS) over-activation is highly involved in cardiovascular diseases (CVDs), with the Gαq-PLCβ3 axis acting as a core node of RAAS. PLCβ3 is a potential target of...
5.
Shen F, Yang W, Luan G, Peng J, Li Z, Gao J, et al.
Phytomedicine . 2024 Jan; 125:155356. PMID: 38241920
Background: Catalpol (CAT), a naturally occurring iridoid glycoside sourced from the root of Rehmannia glutinosa, affects mitochondrial metabolic functions. However, the mechanism of action of CAT against pyrexia and its...
6.
Jiang R, Shen F, Zhang M, Mulati S, Wang J, Tao Y, et al.
Molecules . 2023 Nov; 28(21). PMID: 37959729
Cinnamaldehyde (CA) showed potent activity against melanoma in our previous study, and the structure of unsaturated aldehydes is envisaged to play a role. Nevertheless, its limited drug availability restricts its...
7.
Zhang K, Shen F, Lei W, Han Y, Ma X, Lu Y, et al.
Biomed Pharmacother . 2023 Aug; 166:115323. PMID: 37579692
Dyslipidemia is characterized by elevated levels of total cholesterol and triglycerides in serum, and has become the primary human health killer because of the major risk factors for cardiovascular diseases....
8.
Cheng C, Zhang J, Liu K, Xu Y, Shen F, Han Y, et al.
Phytomedicine . 2023 Jul; 119:154992. PMID: 37499433
Background: Panax ginseng and Panax notoginseng as traditional Chinese medicines, are widely used in the treatment of qi deficiency, viral or bacterial infection, inflammation and cancer. Ginsenoside CK, an active...
9.
Zhang W, Lei W, Shen F, Wang M, Li L, Chang J
Phytother Res . 2023 Apr; 38(10):4957-4966. PMID: 37086182
Colorectal cancer (CRC) is a common malignant tumor with high morbidity and mortality rates worldwide. Although surgical resection and adjuvant radiotherapy/chemotherapy are the mainstays of CRC treatment, the efficacy is...
10.
Cheng C, Liu K, Shen F, Zhang J, Xie Y, Li S, et al.
Phytomedicine . 2023 Apr; 114:154795. PMID: 37030053
Background: Radix Astragali Mongolici, as a traditional Chinese medicine, is widely used in the treatment of qi deficiency, viral or bacterial infection, inflammation and cancer. Astragaloside IV (AST), a key...