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Froylan Gomez-Lagunas

Explore the profile of Froylan Gomez-Lagunas including associated specialties, affiliations and a list of published articles. Areas
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Citations 254
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Recent Articles
1.
Gomez-Lagunas F, Carrillo E, Barriga-Montoya C
Channels (Austin) . 2021 Oct; 15(1):648-665. PMID: 34658293
K ions exert a structural effect that brings stability to K selective pores. Thus, upon bathing Shab channels in 0 K solutions the ion conductance, G, irreversibly collapses. Related to...
2.
Barriga-Montoya C, de la O-Martinez A, Picones A, Hernandez-Cruz A, Fuentes-Pardo B, Gomez-Lagunas F
J Vis Exp . 2019 Nov; (153). PMID: 31762449
A method to study desensitization and recovery of crayfish photoreceptors is presented. We performed intracellular electrical recordings of photoreceptor cells in isolated eyestalks using the discontinuous single electrode-switched voltage-clamp configuration....
3.
Campos-Lira E, Carrillo E, Aguilar M, Gajewiak J, Gomez-Lagunas F, Lopez-Vera E
Toxicon . 2017 Aug; 138:53-58. PMID: 28774677
Conorfamides (CNFs) are toxins initially characterized from the venom duct of the venomous marine snail Conus spurius from the Gulf of Mexico; at their C-termini, these toxins are amidated and...
4.
Barriga-Montoya C, de la O-Martinez A, Fuentes-Pardo B, Gomez-Lagunas F
Comp Biochem Physiol A Mol Integr Physiol . 2016 Nov; 203:297-303. PMID: 27783925
In this work, we studied the characteristics of recovery from desensitization of the light-elicited current of crayfish. Applying a two-flash protocol, we found that the first flash triggers a current...
5.
Gomez-Lagunas F, Carrillo E, Pardo L, Stuhmer W
J Cell Physiol . 2016 Jun; 232(8):2019-2032. PMID: 27255432
Several reports credit mibefradil with tumor suppressing properties arising from its known inhibition of Ca currents. Given that mibefradil (Mb) is also known to inhibit K channels, we decided to...
6.
Carrillo E, Pacheco L, Balleza D, Gomez-Lagunas F
PLoS One . 2015 Mar; 10(3):e0120431. PMID: 25798591
Potassium channels allow the selective flux of K⁺ excluding the smaller, and more abundant in the extracellular solution, Na⁺ ions. Here we show that Shab is a typical K⁺ channel...
7.
Balleza D, Carrillo E, Gomez-Lagunas F
Pflugers Arch . 2014 Nov; 467(10):2069-79. PMID: 25398373
Protein mobility is important to achieve protein function. Intrinsic flexibility associated with motion underlies this important issue and the analysis of side chain flexibility gives insights to understand it. In...
8.
Schwartz E, Bartok A, Schwartz C, Papp F, Gomez-Lagunas F, Panyi G, et al.
Peptides . 2013 May; 46:40-6. PMID: 23684923
Opisthacanthus cayaporum belongs to the Liochelidae family, and the scorpions from this genus occur in southern Africa, Central America and South America and, therefore, can be considered a true Gondwana...
9.
Arias-Olguin I, Carrillo E, Islas L, Gomez-Lagunas F
Channels (Austin) . 2013 Apr; 7(3):225-8. PMID: 23584197
We have recently examined slow inactivation of Shab channels. Here we extend our characterization of Shab slow inactivation by presenting the properties of recovery from inactivation. The observations support our...
10.
Carrillo E, Arias-Olguin I, Islas L, Gomez-Lagunas F
Channels (Austin) . 2013 Feb; 7(2):97-108. PMID: 23419584
Herein, we report the first characterization of Shab slow inactivation. Open Shab channels inactivate within seconds, with two voltage-independent time constants. Additionally, Shab presents significant closed-state inactivation. We found that...