Friedrich Schotte
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Explore the profile of Friedrich Schotte including associated specialties, affiliations and a list of published articles.
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26
Citations
985
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Recent Articles
1.
Schotte F, Cho H, Dyda F, Anfinrud P
Struct Dyn
. 2024 Apr;
11(2):021303.
PMID: 38595979
Photoactive yellow protein (PYP) is a signaling protein whose internal p-coumaric acid chromophore undergoes reversible, light-induced -to- isomerization, which triggers a sequence of structural changes that ultimately lead to a...
2.
Cho H, Schotte F, Stadnytskyi V, Anfinrud P
Curr Opin Struct Biol
. 2021 Jun;
70:99-107.
PMID: 34175665
Time-resolved small- and wide-angle X-ray scattering studies of proteins in solution based on the pump-probe approach unveil structural information from intermediates over a broad range of length and time scales....
3.
Thompson M, Barad B, Wolff A, Cho H, Schotte F, Schwarz D, et al.
Nat Chem
. 2019 Sep;
11(11):1058-1066.
PMID: 31527847
Correlated motions of proteins are critical to function, but these features are difficult to resolve using traditional structure determination techniques. Time-resolved X-ray methods hold promise for addressing this challenge, but...
4.
Cho H, Schotte F, Stadnytskyi V, Dichiara A, Henning R, Anfinrud P
J Phys Chem B
. 2018 Oct;
122(49):11488-11496.
PMID: 30285440
It is well-known that tetrameric hemoglobin binds ligands cooperatively by undergoing a ligand-induced T → R quaternary structure transition, a structure-function relationship that has long served as a model system...
5.
Cho H, Schotte F, Dashdorj N, Kyndt J, Henning R, Anfinrud P
J Am Chem Soc
. 2016 Jun;
138(28):8815-23.
PMID: 27305463
The capacity to respond to environmental changes is crucial to an organism's survival. Halorhodospira halophila is a photosynthetic bacterium that swims away from blue light, presumably in an effort to...
6.
Schotte F, Cho H, Soman J, Wulff M, Olson J, Anfinrud P
Chem Phys
. 2014 May;
422:98-106.
PMID: 24839343
We have developed the method of picosecond Laue crystallography and used this capability to probe ligand dynamics in tetrameric R-state hemoglobin (Hb). Time-resolved, 2 Å-resolution electron density maps of photolyzed...
7.
Kaila V, Schotte F, Cho H, Hummer G, Anfinrud P
Nat Chem
. 2014 Mar;
6(4):258-9.
PMID: 24651178
No abstract available.
8.
Cho H, Schotte F, Dashdorj N, Kyndt J, Anfinrud P
J Phys Chem B
. 2013 Oct;
117(49):15825-32.
PMID: 24125473
We have exploited the principle of photoselection and the method of time-resolved small-angle X-ray scattering (SAXS) to investigate protein size and shape changes following photoactivation of photoactive yellow protein (PYP)...
9.
Schotte F, Cho H, Kaila V, Kamikubo H, Dashdorj N, Henry E, et al.
Proc Natl Acad Sci U S A
. 2012 Nov;
109(47):19256-61.
PMID: 23132943
To understand how signaling proteins function, it is crucial to know the time-ordered sequence of events that lead to the signaling state. We recently developed on the BioCARS 14-IDB beamline...
10.
Cho H, Dashdorj N, Schotte F, Graber T, Henning R, Anfinrud P
Proc Natl Acad Sci U S A
. 2010 Apr;
107(16):7281-6.
PMID: 20406909
We have developed a time-resolved x-ray scattering diffractometer capable of probing structural dynamics of proteins in solution with 100-ps time resolution. This diffractometer, developed on the ID14B BioCARS (Consortium for...