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Frederick Jaeger

Explore the profile of Frederick Jaeger including associated specialties, affiliations and a list of published articles. Areas
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Citations 247
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Recent Articles
1.
Mansour R, Stamper L, Jaeger F, McGuire E, Fouda G, Amos J, et al.
PLoS One . 2016 May; 11(5):e0155261. PMID: 27182834
Tenascin-C (TNC) is a newly identified innate HIV-1-neutralizing protein present in breast milk, yet its presence and potential HIV-inhibitory function in other mucosal fluids is unknown. In this study, we...
2.
Fouda G, Mahlokozera T, Salazar-Gonzalez J, Salazar M, Learn G, Kumar S, et al.
Retrovirology . 2013 Jan; 10:3. PMID: 23305422
Background: Breastfeeding is a leading cause of infant HIV-1 infection in the developing world, yet only a minority of infants exposed to HIV-1 via breastfeeding become infected. As a genetic...
3.
Morris L, Chen X, Alam M, Tomaras G, Zhang R, Marshall D, et al.
PLoS One . 2011 Oct; 6(9):e23532. PMID: 21980336
Broadly neutralizing antibodies are not commonly produced in HIV-1 infected individuals nor by experimental HIV-1 vaccines. When these antibodies do occur, it is important to be able to isolate and...
4.
Alam S, Liao H, Dennison S, Jaeger F, Parks R, Anasti K, et al.
J Virol . 2011 Sep; 85(22):11725-31. PMID: 21917975
Genetic factors, as well as antigenic stimuli, can influence antibody repertoire formation. Moreover, the affinity of antigen for unmutated naïve B cell receptors determines the threshold for activation of germinal...
5.
Shen X, Dennison S, Liu P, Gao F, Jaeger F, Montefiori D, et al.
Proc Natl Acad Sci U S A . 2010 Mar; 107(13):5972-7. PMID: 20231447
The conserved membrane-proximal external region (MPER) of HIV-1 envelope is a target for the rare broadly neutralizing 2F5, Z13, and 4E10 monoclonal antibodies (mAbs). One strategy to elicit such antibodies...