Frederick E Dewey
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Explore the profile of Frederick E Dewey including associated specialties, affiliations and a list of published articles.
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5101
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Recent Articles
1.
De Jong H, Dewey F, Cordero P, Victorio R, Kirillova A, Huang Y, et al.
Circ Genom Precis Med
. 2022 Jun;
15(4):e003563.
PMID: 35671065
Background: The study of hypertrophic cardiomyopathy (HCM) can yield insight into the mechanisms underlying the complex trait of cardiac hypertrophy. To date, most genetic variants associated with HCM have been...
2.
Buchanan A, Manickam K, Meyer M, Wagner J, Hallquist M, Williams J, et al.
Genet Med
. 2021 Oct;
23(12):2470.
PMID: 34646007
No abstract available.
3.
Haggerty C, Damrauer S, Levin M, Birtwell D, Carey D, Golden A, et al.
Circulation
. 2019 Jun;
140(1):42-54.
PMID: 31216868
Background: Truncating variants in the Titin gene (TTNtvs) are common in individuals with idiopathic dilated cardiomyopathy (DCM). However, a comprehensive genomics-first evaluation of the impact of TTNtvs in different clinical...
4.
Flannick J, Mercader J, Fuchsberger C, Udler M, Mahajan A, Wessel J, et al.
Nature
. 2019 May;
570(7759):71-76.
PMID: 31118516
Protein-coding genetic variants that strongly affect disease risk can yield relevant clues to disease pathogenesis. Here we report exome-sequencing analyses of 20,791 individuals with type 2 diabetes (T2D) and 24,440 ...
5.
Peloso G, Nomura A, Khera A, Chaffin M, Won H, Ardissino D, et al.
Circ Genom Precis Med
. 2019 Apr;
12(5):e002376.
PMID: 30939045
Background Familial hypobetalipoproteinemia is a genetic disorder caused by rare protein-truncating variants (PTV) in the gene encoding APOB (apolipoprotein B), the major protein component of LDL (low-density lipoprotein) and triglyceride-rich...
6.
Manickam K, Buchanan A, Schwartz M, Hallquist M, Williams J, Rahm A, et al.
JAMA Netw Open
. 2019 Jan;
1(5):e182140.
PMID: 30646163
Importance: Detection of disease-associated variants in the BRCA1 and BRCA2 (BRCA1/2) genes allows for cancer prevention and early diagnosis in high-risk individuals. Objectives: To identify pathogenic and likely pathogenic (P/LP)...
7.
Choi S, Weng L, Roselli C, Lin H, Haggerty C, Shoemaker M, et al.
JAMA
. 2018 Dec;
320(22):2354-2364.
PMID: 30535219
Importance: Atrial fibrillation (AF) is the most common arrhythmia affecting 1% of the population. Young individuals with AF have a strong genetic association with the disease, but the mechanisms remain...
8.
Bohnen M, Ma L, Zhu N, Qi H, McClenaghan C, Gonzaga-Jauregui C, et al.
Circ Genom Precis Med
. 2018 Oct;
11(10):e002087.
PMID: 30354297
Background: In pulmonary arterial hypertension (PAH), pathological changes in pulmonary arterioles progressively raise pulmonary artery pressure and increase pulmonary vascular resistance, leading to right heart failure and high mortality rates....
9.
Author Correction: Rare variants in drug target genes contributing to complex diseases, phenome-wide
Verma S, Josyula N, Verma A, Zhang X, Veturi Y, Dewey F, et al.
Sci Rep
. 2018 Oct;
8(1):15911.
PMID: 30353015
A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper.
10.
Klarin D, Damrauer S, Cho K, Sun Y, Teslovich T, Honerlaw J, et al.
Nat Genet
. 2018 Oct;
50(11):1514-1523.
PMID: 30275531
The Million Veteran Program (MVP) was established in 2011 as a national research initiative to determine how genetic variation influences the health of US military veterans. Here we genotyped 312,571...