Frederick A Zeiler
Overview
Explore the profile of Frederick A Zeiler including associated specialties, affiliations and a list of published articles.
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177
Citations
2184
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Recent Articles
1.
Silvaggio N, Stein K, Sainbhi A, Vakitbilir N, Bergmann T, Islam A, et al.
Sensors (Basel)
. 2025 Feb;
25(3).
PMID: 39943547
Cerebral blood volume (CBV) is an essential metric that indicates and evaluates various healthy and pathologic conditions. Most methods of CBV measurement are cumbersome and have a poor temporal resolution....
2.
Islam A, Sainbhi A, Stein K, Vakitbilir N, Gomez A, Silvaggio N, et al.
Sensors (Basel)
. 2025 Jan;
25(2).
PMID: 39860955
Goal: Current methodologies for assessing cerebral compliance using pressure sensor technologies are prone to errors and issues with inter- and intra-observer consistency. RAP, a metric for measuring intracranial compensatory reserve...
3.
Donnelly J, Beqiri E, Zeiler F, Smielewski P, Czosnyka M
Brain Spine
. 2025 Jan;
4():102764.
PMID: 39776673
Introduction: Secondary insults due to high intracranial pressure (ICP), low cerebral perfusion pressure (CPP) and impaired cerebral pressure reactivity (PRx) predict outcome after severe traumatic brain injury (TBI). Research Question:...
4.
Vakitbilir N, Islam A, Gomez A, Stein K, Froese L, Bergmann T, et al.
Sensors (Basel)
. 2025 Jan;
24(24.
PMID: 39771880
Monitoring cerebral oxygenation and metabolism, using a combination of invasive and non-invasive sensors, is vital due to frequent disruptions in hemodynamic regulation across various diseases. These sensors generate continuous high-frequency...
5.
Bergmann T, Vakitbilir N, Gomez A, Islam A, Stein K, Sainbhi A, et al.
Physiol Meas
. 2024 Dec;
45(12).
PMID: 39637554
. Intracranial pressure measurement (ICP) is an essential component of deriving of multivariate data metrics foundational to improving understanding of high temporal relationships in cerebral physiology. A significant barrier to...
6.
Lee J, Wang W, Rezk A, Mohammed A, Macabudbud K, Englesakis M, et al.
JAMA Netw Open
. 2024 Nov;
7(11):e2444465.
PMID: 39527054
Importance: Traumatic brain injury (TBI) is a leading cause of death and disability worldwide. Hypotension in patients with TBI is associated with poorer outcomes. A comprehensive review examining adverse outcomes...
7.
Park K, Froese L, Bergmann T, Gomez A, Sainbhi A, Vakitbilir N, et al.
Neurotrauma Rep
. 2024 Oct;
5(1):916-956.
PMID: 39474098
Neurointensive care primarily focuses on secondary injury reduction, utilizing a variety of guideline-based approaches (including administration of high-dose sedation) to reduce the injured state. However, titration of sedation is currently...
8.
Islam A, Marquez I, Froese L, Vakitbilir N, Gomez A, Stein K, et al.
Neurotrauma Rep
. 2024 Oct;
5(1):813-823.
PMID: 39391049
Acute traumatic neural injury, known as traumatic brain injury (TBI), stands as a significant contributor to global mortality and disability. Ideally, continuously monitoring cerebral compliance/cerebral compensatory reserve would enable timely...
9.
Friberg S, Lindblad C, Zeiler F, Zetterberg H, Granberg T, Svenningsson P, et al.
Nat Rev Neurol
. 2024 Oct;
20(11):671-684.
PMID: 39363129
Traumatic brain injury (TBI) is a leading cause of long-term disability across the world. Evidence for the usefulness of imaging and fluid biomarkers to predict outcomes and screen for the...
10.
Bergmann T, Vakitbilir N, Gomez A, Islam A, Stein K, Sainbhi A, et al.
Bioengineering (Basel)
. 2024 Sep;
11(9).
PMID: 39329675
Artifacts induced during patient monitoring are a main limitation for near-infrared spectroscopy (NIRS) as a non-invasive method of cerebral hemodynamic monitoring. There currently does not exist a robust "gold-standard" method...