Frederic Pont
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Explore the profile of Frederic Pont including associated specialties, affiliations and a list of published articles.
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54
Citations
979
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Recent Articles
1.
Driche E, Badji B, Bijani C, Belghit S, Pont F, Mathieu F, et al.
Int Microbiol
. 2024 May;
28(2):241-255.
PMID: 38777925
Introduction: The emergence of multidrug-resistant bacteria and biofilms requires discovering new antimicrobial agents from unexplored environments. Objectives: This study aims to isolate and characterize a new actinobacterial strain from the...
2.
Lumeau A, Bery N, Frances A, Gayral M, Labrousse G, Ribeyre C, et al.
Cancer Res
. 2024 Jan;
84(7):1013-1028.
PMID: 38294491
Significance: Cytidine deaminase reduces replication stress and regulates DNA replication to confer resistance to DNA-damaging drugs in pancreatic cancer, unveiling a molecular vulnerability that could enhance treatment response.
3.
Curdy N, Lanvin O, Cerapio J, Pont F, Tosolini M, Sarot E, et al.
Cell Rep
. 2023 Mar;
42(3):112211.
PMID: 36884350
Stress granules (SGs) and processing bodies (PBs) are membraneless cytoplasmic assemblies regulating mRNAs under environmental stress such as viral infections, neurological disorders, or cancer. Upon antigen stimulation, T lymphocytes mediate...
4.
Pont F, Cerapio J, Gravelle P, Ligat L, Valle C, Sarot E, et al.
BMC Bioinformatics
. 2023 Jan;
24(1):30.
PMID: 36707753
Background: The development of single-cell technologies yields large datasets of information as diverse and multimodal as transcriptomes, immunophenotypes, and spatial position from tissue sections in the so-called 'spatial transcriptomics'. Currently...
5.
Maillard M, Arellano C, Vachoux C, Chevreau C, Cabaton N, Pont F, et al.
Metabolites
. 2022 Sep;
12(9).
PMID: 36144257
Tyrosine kinase inhibitors pazopanib and sunitinib are both used to treat advanced renal cell carcinoma but expose patients to an increased risk of hepatotoxicity. We have previously identified two aldehyde...
6.
Driche E, Badji B, Bijani C, Belghit S, Pont F, Mathieu F, et al.
Curr Microbiol
. 2022 Aug;
79(10):298.
PMID: 36002540
Multi-resistant bacterial pathogens are a major public health problem for treating nosocomial infections owing to their high resistance to antibiotics. The objective of this research was to characterize the bioactive...
7.
Single-Cell RNAseq Profiling of Human γδ T Lymphocytes in Virus-Related Cancers and COVID-19 Disease
Cerapio J, Perrier M, Pont F, Tosolini M, Laurent C, Bertani S, et al.
Viruses
. 2021 Nov;
13(11).
PMID: 34835019
The detailed characterization of human γδ T lymphocyte differentiation at the single-cell transcriptomic (scRNAseq) level in tumors and patients with coronavirus disease 2019 (COVID-19) requires both a reference differentiation trajectory...
8.
Cerapio J, Perrier M, Balanca C, Gravelle P, Pont F, Devaud C, et al.
Oncoimmunology
. 2021 Nov;
10(1):1939518.
PMID: 34721945
γδ T lymphocytes diverge from conventional T CD8 lymphocytes for ontogeny, homing, and antigen specificity, but whether their differentiation in tumors also deviates was unknown. Using innovative analyses of our...
9.
Cintas C, Douche T, Dantes Z, Mouton-Barbosa E, Bousquet M, Cayron C, et al.
Mol Cancer Ther
. 2021 Sep;
20(12):2433-2445.
PMID: 34552006
The PI3K pathway is highly active in human cancers. The four class I isoforms of PI3K are activated by distinct mechanisms leading to a common downstream signaling. Their downstream redundancy...
10.
Ysebaert L, Quillet-Mary A, Tosolini M, Pont F, Laurent C, Fournie J
Front Immunol
. 2021 Mar;
12:597651.
PMID: 33732232
High-definition transcriptomic studies through single-cell RNA sequencing (scRNA-Seq) have revealed the heterogeneity and functionality of the various microenvironments across numerous solid tumors. Those pioneer studies have highlighted different cellular signatures...