Frederic Larrieu-Lahargue
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Explore the profile of Frederic Larrieu-Lahargue including associated specialties, affiliations and a list of published articles.
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16
Citations
765
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Recent Articles
1.
Guillabert-Gourgues A, Jaspard-Vinassa B, Bats M, Sewduth R, Franzl N, Peghaire C, et al.
Mol Biol Cell
. 2016 Jan;
27(6):941-53.
PMID: 26792835
Angiogenesis involves the coordinated growth and migration of endothelial cells (ECs) toward a proangiogenic signal. The Wnt planar cell polarity (PCP) pathway, through the recruitment of Dishevelled (Dvl) and Dvl-associated...
2.
Chapouly C, Yao Q, Vandierdonck S, Larrieu-Lahargue F, Mariani J, Gadeau A, et al.
Cardiovasc Res
. 2015 Dec;
109(2):217-27.
PMID: 26645982
Aims: Microangiopathy, i.e. endothelial dysfunction, has long been suggested to contribute to the development of diabetic neuropathy, although this has never been fully verified. In the present paper, we have...
3.
Sewduth R, Jaspard-Vinassa B, Peghaire C, Guillabert A, Franzl N, Larrieu-Lahargue F, et al.
Nat Commun
. 2014 Sep;
5:4832.
PMID: 25198863
Development and stabilization of a vascular plexus requires the coordination of multiple signalling processes. Wnt planar cell polarity (PCP) signalling is critical in vertebrates for diverse morphogenesis events, which coordinate...
4.
Ferreira Tojais N, Peghaire C, Franzl N, Larrieu-Lahargue F, Jaspard B, Reynaud A, et al.
Cardiovasc Res
. 2014 May;
103(2):291-303.
PMID: 24866384
Aims: Vascular permeability is essential for the health of normal tissues and is an important characteristic of many disease states. The role of the Wnt/frizzled pathway in vascular biology has...
5.
Renault M, Chapouly C, Yao Q, Larrieu-Lahargue F, Vandierdonck S, Reynaud A, et al.
Circ Res
. 2013 Jan;
112(5):762-70.
PMID: 23343527
Rationale: Blood vessel growth and patterning have been shown to be regulated by nerve-derived signals. Desert hedgehog (Dhh), one of the Hedgehog family members, is expressed by Schwann cells of...
6.
Larrieu-Lahargue F, Thomas K, Li D
Trends Cardiovasc Med
. 2012 Jul;
22(2):44-7.
PMID: 22841834
Netrins were initially identified as secreted ligands regulating axon guidance and migration through interaction with canonical receptors. Netrins were then shown to be necessary for development of a range of...
7.
Larrieu-Lahargue F, Welm A, Bouchecareilh M, Alitalo K, Li D, Bikfalvi A, et al.
PLoS One
. 2012 Jul;
7(6):e39540.
PMID: 22761819
Fibroblast Growth Factor receptor (FGFR) activity plays crucial roles in tumor growth and patient survival. However, FGF (Fibroblast Growth Factor) signaling as a target for cancer therapy has been under-investigated...
8.
Larrieu-Lahargue F, Welm A, Thomas K, Li D
Circ Res
. 2011 Jul;
109(7):770-4.
PMID: 21799154
Rationale: Netrin-4 regulates vascular development. Identity of netrin-4 endothelial receptor and its subsequent cell functions is controversial. We previously demonstrated that the inhibition of netrin-1 canonical receptors, Unc5B and neogenin,...
9.
Wende A, Soto J, Olsen C, Pires K, Schell J, Larrieu-Lahargue F, et al.
Endocrinology
. 2010 May;
151(8):3536-42.
PMID: 20501666
Bradykinin signaling has been proposed to play either protective or deleterious roles in the development of cardiac dysfunction in response to various pathological stimuli. To further define the role of...
10.
Larrieu-Lahargue F, Welm A, Thomas K, Li D
Blood
. 2010 Apr;
115(26):5418-26.
PMID: 20407033
Netrin-4, a laminin-related secreted protein is an axon guidance cue recently shown essential outside of the nervous system, regulating mammary and lung morphogenesis as well as blood vascular development. Here,...