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Frederic Dayan

Explore the profile of Frederic Dayan including associated specialties, affiliations and a list of published articles. Areas
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Articles 14
Citations 1410
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11.
Dayan F, Bilton R, Laferriere J, Trottier E, Roux D, Pouyssegur J, et al.
J Cell Physiol . 2008 Sep; 218(1):167-74. PMID: 18781596
Accumulation of HIF-1alpha during normoxic conditions at high cell density has previously been shown to occur and can be used to stabilize HIF-1alpha protein in the absence of a specific...
12.
Pouyssegur J, Dayan F, Mazure N
Nature . 2006 May; 441(7092):437-43. PMID: 16724055
Tumour cells emerge as a result of genetic alteration of signal circuitries promoting cell growth and survival, whereas their expansion relies on nutrient supply. Oxygen limitation is central in controlling...
13.
Dayan F, Roux D, Brahimi-Horn M, Pouyssegur J, Mazure N
Cancer Res . 2006 Apr; 66(7):3688-98. PMID: 16585195
The function of the hypoxia-inducible factor-1 (HIF-1), the key transcription factor involved in cellular adaptation to hypoxia, is restricted to low oxygen tension (pO(2)). As such, this transcription factor is...
14.
Mazure N, Brahimi-Horn M, Berta M, Benizri E, Bilton R, Dayan F, et al.
Biochem Pharmacol . 2004 Aug; 68(6):971-80. PMID: 15313390
The hypoxia-inducible factor-1 (HIF-1) is primarily involved in the sensing and adapting of cells to changes in the O2 level, which is essential for their viability. It is important that...