Fred J Roisen
Overview
Explore the profile of Fred J Roisen including associated specialties, affiliations and a list of published articles.
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Articles
12
Citations
182
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Recent Articles
1.
Gao Y, Winstead W, Lei Z, Lu C, Roisen F, El-Mallakh R
J Cent Nerv Syst Dis
. 2017 May;
9:1179573517694529.
PMID: 28469524
Background: Research into the pathophysiology of bipolar disorder (BD) is limited by the inability to examine brain cellular processes in subjects with the illness. Methods: Endoscopic biopsy was performed in...
2.
Gao Y, Lei Z, Lu C, Roisen F, El-Mallakh R
World J Biol Psychiatry
. 2010 Aug;
11(8):972-84.
PMID: 20799912
Objectives: Disturbed ion homeostasis and apoptosis have been implicated in the pathophysiology of bipolar disorder (BD). TRPM2, a nonselective cation channel, is involved in apoptosis and is possibly linked with...
3.
Willett L, Gao Y, Lei Z, Lu C, Roisen F, Winstead W, et al.
Psychiatry Res
. 2010 May;
178(2):391-4.
PMID: 20472302
Low levels of brain-derived neurotrophic factor (BDNF) peptide are linked to the pathophysiology of mood disorders. Several single-nucleotide polymorphisms (SNPs) across the BDNF gene (BDNF) have been associated with bipolar...
4.
Xiao M, Klueber K, Zhou J, Guo Z, Lu C, Wang H, et al.
Neurobiol Dis
. 2007 Mar;
26(2):363-74.
PMID: 17346980
We investigated the effects of engrafted human adult olfactory neuroepithelial neurosphere forming cells (NSFCs) on regeneration and reinnervation of rubrospinal tract (RST) axons and locomotor recovery following partial cervical hemisection...
5.
Zhang X, Klueber K, Guo Z, Cai J, Lu C, Winstead W, et al.
Brain Res
. 2006 Feb;
1073-1074:109-19.
PMID: 16455065
Neurosphere forming cells (NSFCs) have been established from cultures of adult olfactory neuroepithelium obtained from patients and cadavers as described previously. They remained undifferentiated in serum or defined media with...
6.
Zhang X, Cai J, Klueber K, Guo Z, Lu C, Winstead W, et al.
Stem Cells
. 2005 Sep;
24(2):434-42.
PMID: 16141360
Neurosphereforming cell (NSFC) lines have been established from cultures of human adult olfactory neuroepithelium. Few of these cells ever express mature neuronal or glial markers in minimal essential medium supplemented...
7.
Xiao M, Klueber K, Lu C, Guo Z, Marshall C, Wang H, et al.
Exp Neurol
. 2005 May;
194(1):12-30.
PMID: 15899240
Previously, our lab reported the isolation of patient-specific neurosphere-forming progenitor lines from human adult olfactory epithelium from cadavers as well as patients undergoing nasal sinus surgery. RT-PCR and ELISA demonstrated...
8.
Marshall C, Guo Z, Lu C, Klueber K, Khalyfa A, Cooper N, et al.
Brain Res
. 2005 May;
1045(1-2):45-56.
PMID: 15885668
Olfactory epithelium (OE) contains a population of progenitors responsible for its life-long regenerative capacity. Procedures for the isolation of these progenitors have been established [F.J. Roisen, K.M. Klueber, C.L. Lu,...
9.
Winstead W, Marshall C, Lu C, Klueber K, Roisen F
Am J Rhinol
. 2005 Mar;
19(1):83-90.
PMID: 15794081
Background: The adult central nervous system contains progenitor cells; however, invasive surgery is required for their harvest. Olfactory neuroepithelium (ONe) has attracted attention because it is extracranial and contains progenitor...
10.
Zhang X, Cai J, Klueber K, Guo Z, Lu C, Qiu M, et al.
Stem Cells
. 2005 Mar;
23(3):442-53.
PMID: 15749939
Neurosphere-forming cell (NSFC) lines have been derived from cultures of adult olfactory neuroepithelium obtained from patients and cadavers. These progenitors remain undifferentiated when maintained in minimal essential medium with 10%...