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Fred F Kadlubar

Explore the profile of Fred F Kadlubar including associated specialties, affiliations and a list of published articles. Areas
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Articles 70
Citations 1818
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Recent Articles
1.
Zhang X, Huang M, Wu X, Kadlubar S, Lin J, Yu X, et al.
Pharmgenomics Pers Med . 2013 Mar; 6:9-17. PMID: 23526580
The objective of this study was to determine copy number variant (CNV) and promoter genetic variants in glutathione S-transferase Mu class 1 (GSTM1) and the risk of recurrence (REC)/second primary...
2.
Zhang X, Lin J, Wu X, Lin Z, Ning B, Kadlubar S, et al.
Int J Mol Epidemiol Genet . 2012 Oct; 3(3):228-36. PMID: 23050053
This study sought to determine the role of copy number variants (CNV) combined with other genetic variants in the Glutathione S-transferases Mu class1 (GSTM1) promoter in the development of urinary...
3.
Zhang J, Zhang X, Dhakal I, Gross M, Kadlubar F, Anderson K
Int J Mol Epidemiol Genet . 2011 Sep; 2(3):236-44. PMID: 21915362
To investigate whether polymorphisms in genes related to oxidative stress act alone or in combination with antioxidants to modulate pancreatic cancer risk. Cases (n=189), ages ≥ 20 years, were ascertained...
4.
Mercer K, Apostolov E, Gamboa da Costa G, Yu X, Lang P, Roberts D, et al.
Int J Mol Epidemiol Genet . 2011 May; 1(2):92-103. PMID: 21537383
Previously, we reported a strong association of the high activity SULT1A1*1 allele and overall survival of patients receiving tamoxifen therapy, indicating that sulfation of 4-hydroxytamoxifen (4-OHT) via SULT1A1 may contribute...
5.
Gu D, Raymundo M, Kadlubar F, Turesky R
Anal Chem . 2011 Jan; 83(3):1093-101. PMID: 21194225
The cooked meat carcinogens 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP), 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx), and their principal metabolites produced by cytochrome P450 and/or uridine diphosphate glucuronosyl transferases were simultaneously measured at the parts per trillion level...
6.
Yu X, Dhakal I, Beggs M, Edavana V, Williams S, Zhang X, et al.
Toxicol Sci . 2010 Oct; 118(2):391-403. PMID: 20881232
Sulfotransferase isoform 1A1 (SULT1A1) is the most highly expressed hepatic sulfotransferase and is involved in the biotransformation of a wide variety of endo- and xenobiotics. A common single nucleotide polymorphism...
7.
Bessette E, Spivack S, Goodenough A, Wang T, Pinto S, Kadlubar F, et al.
Chem Res Toxicol . 2010 May; 23(7):1234-44. PMID: 20443584
DNA adducts of carcinogens derived from tobacco smoke and cooked meat were identified by liquid chromatography-electrospray ionization/multistage tandem mass spectrometry (LC-ESI/MS/MS(n)) in saliva samples from 37 human volunteers on unrestricted...
8.
Zhang J, Dhakal I, Lang N, Kadlubar F
Cancer Causes Control . 2010 May; 21(9):1437-44. PMID: 20431935
Background: Presence of xenotropic murine leukemia virus-related virus and chronic inflammation in prostate tumor suggests that inflammation plays a role in prostate cancer etiology. This study investigated whether variants in...
9.
Gu D, McNaughton L, LeMaster D, Lake B, Gooderham N, Kadlubar F, et al.
Chem Res Toxicol . 2010 Mar; 23(4):788-801. PMID: 20192249
A targeted liquid chromatography/tandem mass spectrometry-based metabolomics type approach, employing a triple stage quadrupole mass spectrometer in the product ion scan and selected reaction monitoring modes, was established to profile...
10.
Zhang J, Dhakal I, Greene G, Lang N, Kadlubar F
Urology . 2009 Nov; 75(4):779-85. PMID: 19914697
Objectives: To investigate whether polymorphisms in genes involved in the repair of oxidative DNA damage, modulate, and/or interact with antioxidants to influence prostate cancer risk in a population-based case-control study...