Frauke Focke
Overview
Explore the profile of Frauke Focke including associated specialties, affiliations and a list of published articles.
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Articles
5
Citations
244
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Recent Articles
1.
Schuermann D, Ziemann C, Barekati Z, Capstick M, Oertel A, Focke F, et al.
Genes (Basel)
. 2020 Mar;
11(4).
PMID: 32218170
Modulated electromagnetic fields (wEMFs), as generated by modern communication technologies, have raised concerns about adverse health effects. The International Agency for Research on Cancer (IARC) classifies them as "possibly carcinogenic...
2.
Focke F, Schuermann D, Kuster N, Schar P
Mutat Res
. 2009 Nov;
683(1-2):74-83.
PMID: 19896957
Extremely low frequency electromagnetic fields (ELF-EMFs) were reported to affect DNA integrity in human cells with evidence based on the Comet assay. These findings were heavily debated for two main...
3.
Kunz C, Focke F, Saito Y, Schuermann D, Lettieri T, Selfridge J, et al.
PLoS Biol
. 2009 May;
7(4):e91.
PMID: 19402749
5-Fluorouracil (5-FU), a chemotherapeutic drug commonly used in cancer treatment, imbalances nucleotide pools, thereby favoring misincorporation of uracil and 5-FU into genomic DNA. The processing of these bases by DNA...
4.
Hardeland U, Kunz C, Focke F, Szadkowski M, Schar P
Nucleic Acids Res
. 2007 May;
35(11):3859-67.
PMID: 17526518
Human Thymine-DNA Glycosylase (TDG) is a member of the uracil DNA glycosylase (UDG) superfamily. It excises uracil, thymine and a number of chemical base lesions when mispaired with guanine in...
5.
El-Andaloussi N, Valovka T, Toueille M, Steinacher R, Focke F, Gehrig P, et al.
Mol Cell
. 2006 Apr;
22(1):51-62.
PMID: 16600869
Alterations in DNA repair lead to genomic instability and higher risk of cancer. DNA base excision repair (BER) corrects damaged bases, apurinic sites, and single-strand DNA breaks. Here, a regulatory...