Franz Bruckert
Overview
Explore the profile of Franz Bruckert including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
39
Citations
499
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0
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Recent Articles
1.
Alvarez-Palencia Jimenez R, Maze A, Bruckert F, Bensaid F, El-Kechai N, Weidenhaupt M
Eur J Pharm Biopharm
. 2024 Oct;
205:114539.
PMID: 39437981
Biopharmaceuticals, specifically antibody-based therapeutics, have revolutionized disease treatment. Throughout their lifecycle, these therapeutic proteins are exposed to several stress conditions, for example at interfaces, posing a risk to the drug...
2.
Alvarez-Palencia Jimenez R, Maze A, Vian G, Bruckert F, Bensaid F, El-Kechai N, et al.
Eur J Pharm Biopharm
. 2024 Jul;
203:114425.
PMID: 39059751
Monoclonal antibodies (mAbs) encounter numerous interfaces during manufacturing, storage, and administration. While protein adsorption at the solid/liquid interface has been widely explored on model surfaces, a key challenge remains -...
3.
Marichal L, Bagnard L, Sire O, Vendrely C, Bruckert F, Weidenhaupt M
Biochim Biophys Acta Gen Subj
. 2023 Aug;
1867(11):130450.
PMID: 37640168
Functional amyloids are commonly produced by many microorganisms and their biological functions are numerous. Staphylococcus aureus can secrete a group of peptides named phenol-soluble modulins (PSMs) in their biofilm extracellular...
4.
Valat A, Fourel L, Sales A, Machillot P, Bouin A, Fournier C, et al.
Front Cell Dev Biol
. 2023 Jan;
10:1027334.
PMID: 36684447
Upon BMP-2 stimulation, the osteoblastic lineage commitment in C2C12 myoblasts is associated with a microenvironmental change that occurs over several days. How does BMP-2 operate a switch in adhesive machinery...
5.
Chouchane K, Frachon T, Marichal L, Nault L, Vendrely C, Maze A, et al.
Colloids Surf B Biointerfaces
. 2022 Mar;
214:112451.
PMID: 35290820
The consequences of agitation on protein stability are particularly relevant to therapeutic proteins. However, the precise contribution of the different effects induced by agitation in pathways leading to protein denaturation...
6.
Lefebvre G, Maze A, Alvarez-Palencia Jimenez R, Bruckert F, Filipe V, Huille S, et al.
Pharm Res
. 2021 Dec;
38(12):2157-2166.
PMID: 34904200
Objective: Monoclonal antibodies are in contact with many different materials throughout their life cycle from production to patient administration. Plastic surfaces are commonly found in single use bags, syringes, perfusion...
7.
Lefebvre G, Bruckert F, Filipe V, Huille S, Weidenhaupt M
Colloids Surf B Biointerfaces
. 2021 Apr;
203:111722.
PMID: 33839475
Adsorption of therapeutic proteins to material surfaces can be a pivotal issue in drug development, especially for low concentration products. Surfactants are used to limit adsorption losses. For each formulation...
8.
Reczynska K, Major R, Kopernik M, Pamula E, Imbir G, Plutecka H, et al.
Colloids Surf B Biointerfaces
. 2021 Feb;
201:111624.
PMID: 33621749
The main purpose of the work was to develop a drug releasing coatings on the surface of medical devices exposed to blood flow, what should enable effective inhibition of blood...
9.
Sattler N, Bosmani C, Barisch C, Gueho A, Gopaldass N, Dias M, et al.
J Cell Sci
. 2018 Jul;
131(17).
PMID: 30054386
Phagocytic cells take up, kill and digest microbes by a process called phagocytosis. To this end, these cells bind the particle, rearrange their actin cytoskeleton, and orchestrate transport of digestive...
10.
Chouchane K, Pignot-Paintrand I, Bruckert F, Weidenhaupt M
J Photochem Photobiol B
. 2018 Mar;
181:89-97.
PMID: 29524850
Insulin is known to form amyloid aggregates when agitated in a hydrophobic container. Amyloid aggregation is routinely measured by the fluorescence of the conformational dye thioflavin T, which, when incorporated...