Frans Stellaard
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Explore the profile of Frans Stellaard including associated specialties, affiliations and a list of published articles.
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79
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1112
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Recent Articles
1.
Stellaard F, Lutjohann D
Nutrients
. 2025 Feb;
17(4).
PMID: 40004982
Elevated plasma low-density lipoprotein cholesterol (LDL-C) is associated with an increased risk for atherosclerosis and development of cardiovascular disease. An elevated plasma LDL-C concentration is the result of enhanced C...
2.
Sosic-Jurjevic B, Borkovic-Mitic S, Pavlovic S, Vlahovic D, Miler M, Cesar T, et al.
Int J Mol Sci
. 2024 May;
25(10).
PMID: 38791260
This study aimed to assess the antioxidant capacity of lemon flavonoid extract Eriomin (LE) and its impact on cholesterol metabolism in the context of healthy aging. We orally treated 24-month-old...
3.
Lutjohann D, Stellaard F
Int J Clin Pharmacol Ther
. 2024 May;
62(7):295-306.
PMID: 38699976
Objective: We questioned whether the baseline status of low-density lipoprotein cholesterol (LDL-C), cholesterol synthesis and absorption, and the changes in these parameters determine the change in serum LDL-C under statin...
4.
Stellaard F
Nutrients
. 2023 Jul;
15(14).
PMID: 37513504
The ' Special Issue "From dietary cholesterol to blood cholesterol" aims to supply existing knowledge and novel new research data about human cholesterol (C) fluxes [...].
5.
Lutjohann D, Klor H, Stellaard F
Nutrients
. 2023 Jul;
15(9).
PMID: 37432317
The serum low density lipoprotein cholesterol (LDL-C) concentration is the dominant clinical parameter to judge a patient's risk of developing cardiovascular disease (CVD). Recent evidence supports the theory that cholesterol...
6.
Stellaard F, Baumgartner S, Mensink R, Winkens B, Plat J, Lutjohann D
Nutrients
. 2022 Dec;
14(24).
PMID: 36558527
Introduction. Pharmacological reduction of cholesterol (C) synthesis and C absorption lowers serum low-density lipoprotein C (LDL-C) concentrations. We questioned whether high baseline C synthesis or C absorption translates into high...
7.
Di Ciaula A, Bonfrate L, Baj J, Khalil M, Garruti G, Stellaard F, et al.
Nutrients
. 2022 Dec;
14(23).
PMID: 36500979
Bile acids (BA) are amphiphilic molecules synthesized in the liver (primary BA) starting from cholesterol. In the small intestine, BA act as strong detergents for emulsification, solubilization and absorption of...
8.
Stellaard F
Nutrients
. 2022 Apr;
14(8).
PMID: 35458205
Dietary cholesterol (C) is a major contributor to the endogenous C pool, and it affects the serum concentration of total C, particularly the low-density lipoprotein cholesterol (LDL-C). A high serum...
9.
Stellaard F, Lutjohann D
Am J Physiol Gastrointest Liver Physiol
. 2021 May;
321(1):G55-G66.
PMID: 33978477
Regulation of bile acid metabolism is normally discussed as the regulation of bile acid synthesis, which serves to compensate for intestinal loss in order to maintain a constant pool size....
10.
Lutjohann D, Stellaard F, Bolukbasi B, Kerksiek A, Parhofer K, Laufs U
Br J Clin Pharmacol
. 2021 Apr;
87(11):4252-4261.
PMID: 33792095
Aims: The serum ratios of the brain-specific oxysterol 24S-hydroxycholesterol (24S-OHC) to cholesterol and to 27-OHC reflect brain cholesterol turnover. We studied the effect of proprotein convertase subtilisin/kexin type 9 monoclonal...