Frans M Helmerhorst
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Explore the profile of Frans M Helmerhorst including associated specialties, affiliations and a list of published articles.
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73
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1415
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Recent Articles
1.
Verlaan J, Stegeman B, Timp J, Scheres L, Flinterman L, Helmerhorst F, et al.
J Thromb Haemost
. 2024 Mar;
22(8):2195-2202.
PMID: 38554933
Background: Extensive evidence is available on hormonal contraceptive (HC) use and the risk of a first venous thromboembolism (VTE) event. Despite recommendations to discontinue combined HC (CHC) use, some women...
2.
Stegeman B, Vos H, Helmerhorst F, Rosendaal F, Reitsma P, van Hylckama Vlieg A
Eur J Intern Med
. 2017 Jun;
42:54-60.
PMID: 28579309
Background: Use of ethinylestradiol, one of the active ingredients in combined oral contraceptives, affects the incidence of venous thrombosis. To explain why some women develop thrombosis when using oral contraceptives...
3.
He N, Van Iperen L, de Jong D, Szuhai K, Helmerhorst F, van der Westerlaken L, et al.
PLoS One
. 2017 Jan;
12(1):e0169849.
PMID: 28081266
In humans, the defective invasion of the maternal endometrium by fetal extravillous trophoblasts (EVTs) can lead to insufficient perfusion of the placenta, resulting in pregnancy complications that can put both...
4.
van der Weiden R, Helmerhorst F, Eriksson T
BMJ Case Rep
. 2016 Sep;
2016.
PMID: 27655876
Aggression in patients with autism spectrum disorder (ASD) presents an important therapeutic challenge. Conventional treatment appears to be inadequate in a number of cases. The occurrence of severe aggressive symptoms...
5.
Lopez L, Ramesh S, Chen M, Edelman A, Otterness C, Trussell J, et al.
Cochrane Database Syst Rev
. 2016 Aug;
(8):CD008815.
PMID: 27567593
Background: Progestin-only contraceptives (POCs) are appropriate for many women who cannot or should not take estrogen. POCs include injectables, intrauterine contraception, implants, and oral contraceptives. Many POCs are long-acting, cost-effective...
6.
Lopez L, Bernholc A, Chen M, Grey T, Otterness C, Westhoff C, et al.
Cochrane Database Syst Rev
. 2016 Aug;
(8):CD008452.
PMID: 27537097
Background: Obesity has reached epidemic proportions around the world. Effectiveness of hormonal contraceptives may be related to metabolic changes in obesity or to greater body mass or body fat. Hormonal...
7.
Roach R, Helmerhorst F, Lijfering W, Stijnen T, Algra A, Dekkers O
Cochrane Database Syst Rev
. 2015 Aug;
(8):CD011054.
PMID: 26310586
Background: Combined oral contraceptives (COCs) have been associated with an increased risk of arterial thrombosis, i.e. myocardial infarction or ischemic stroke. However, as these diseases are rare in young women...
8.
Lopez L, Chen M, Mullins Long S, Curtis K, Helmerhorst F
Cochrane Database Syst Rev
. 2015 Jul;
(7):CD009849.
PMID: 26195091
Background: Age-related decline in bone mass increases the risk of skeletal fractures, especially those of the hip, spine, and wrist. Steroidal contraceptives have been associated with changes in bone mineral...
9.
Heeren A, Van Iperen L, Klootwijk D, Bernardo A, Roost M, Gomes Fernandes M, et al.
BMC Dev Biol
. 2015 Jan;
15:4.
PMID: 25605128
Background: In society, there is a clear need to improve the success rate of techniques to restore fertility. Therefore a deeper knowledge of the dynamics of the complex molecular environment...
10.
de Bastos M, Stegeman B, Rosendaal F, van Hylckama Vlieg A, Helmerhorst F, Stijnen T, et al.
Cochrane Database Syst Rev
. 2014 Mar;
(3):CD010813.
PMID: 24590565
Background: Combined oral contraceptive (COC) use has been associated with venous thrombosis (VT) (i.e., deep venous thrombosis and pulmonary embolism). The VT risk has been evaluated for many estrogen doses...