Frank van der Hoeven
Overview
Explore the profile of Frank van der Hoeven including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
459
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0
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Recent Articles
1.
Sobotta S, Raue A, Huang X, Vanlier J, Junger A, Bohl S, et al.
Front Physiol
. 2017 Oct;
8:775.
PMID: 29062282
IL-6 is a central mediator of the immediate induction of hepatic acute phase proteins (APP) in the liver during infection and after injury, but increased IL-6 activity has been associated...
2.
Zhang W, Freichel M, van der Hoeven F, Nawroth P, Katus H, Kalble F, et al.
PLoS One
. 2016 Jan;
11(1):e0145513.
PMID: 26760974
The water channel aquaporin-1 (AQP1) mediates about 50% ultrafiltration during a 2-hour hypertonic dwell in global AQP1 knockout (AQP1-/-) mice. Although AQP1 is widely expressed in various cell types including...
3.
Krieg P, Rosenberger S, de Juanes S, Latzko S, Hou J, Dick A, et al.
J Invest Dermatol
. 2012 Jul;
133(1):172-80.
PMID: 22832496
Loss-of-function mutations in the lipoxygenase (LOX) genes ALOX12B and ALOXE3 are the second most common cause of autosomal recessive congenital ichthyosis. The encoded proteins, 12R-LOX and epidermal LOX-3 (eLOX-3), act...
4.
Kirilov M, Chai M, van der Hoeven F, Kloz U, Schmid W, Schutz G
Transgenic Res
. 2007 Aug;
16(6):783-93.
PMID: 17682835
We have used a lentiviral delivery system (LentiLox3.7) to generate transgenic mice harbouring RNA interference (RNAi) against the hepatocyte nuclear factor 4 gamma (HNF4gamma). HNF4gamma is a nuclear receptor with...
5.
Glaser S, Schaft J, Lubitz S, Vintersten K, van der Hoeven F, Tufteland K, et al.
Development
. 2006 Mar;
133(8):1423-32.
PMID: 16540515
Epigenesis is the process whereby the daughters of a dividing cell retain a chromatin state determined before cell division. The best-studied cases involve the inheritance of heterochromatic chromosomal domains, and...
6.
Testa G, Schaft J, van der Hoeven F, Glaser S, Anastassiadis K, Zhang Y, et al.
Genesis
. 2004 Mar;
38(3):151-8.
PMID: 15048813
Alteration of the mouse genome through homologous recombination in embryonic stem (ES) cells is the most accurate and versatile way to dissect gene function in a vertebrate model. Most often,...
7.
Herrmann T, Muckenthaler M, van der Hoeven F, Brennan K, Gehrke S, Hubert N, et al.
J Mol Med (Berl)
. 2003 Nov;
82(1):39-48.
PMID: 14618243
Patients suffering from hereditary hemochromatosis (HH) show progressive iron overload as a consequence of increased duodenal iron absorption. It has been hypothesized that mutations in the HH gene HFE cause...
8.
Herrmann T, van der Hoeven F, Grone H, Stewart A, Langbein L, Kaiser I, et al.
J Cell Biol
. 2003 Jun;
161(6):1105-15.
PMID: 12821645
The fatty acid transport protein family is a group of evolutionarily conserved proteins that are involved in the cellular uptake and metabolism of long and very long chain fatty acids....