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Frank J Hernandez

Explore the profile of Frank J Hernandez including associated specialties, affiliations and a list of published articles. Areas
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Articles 31
Citations 519
Followers 0
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Recent Articles
1.
Hernandez F
Immunology . 2024 Dec; 174(3):279-286. PMID: 39686519
The story of nucleases begins on the ancient battlefields of early Earth, where simple bacteria fought to survive against viral invaders. Nucleases are enzymes that degrade nucleic acids, with restriction...
2.
Zhang Y, Hu C, McGillicuddy Jr D, Barnes B, Liu Y, Kourafalou V, et al.
Harmful Algae . 2024 Feb; 132:102566. PMID: 38331538
Pelagic Sargassum in the Gulf of Mexico (GoM) plays an important role in ocean biology and ecology, yet our knowledge of its origins and transport pathways is limited. Here, using...
3.
Goikoetxea G, Akhtar K, Prysiazhniuk A, Borsa B, Aldag M, Kavruk M, et al.
Analyst . 2024 Jan; 149(4):1289-1296. PMID: 38240377
() represents a significant pathogenic threat, often responsible for community-acquired pneumonia with potentially life-threatening consequences if left untreated. This underscores the pressing clinical need for rapid and accurate detection of...
4.
Borsa B, Hernandez L, Jimenez T, Tellapragada C, Giske C, Hernandez F
J Control Release . 2023 Aug; 361:260-269. PMID: 37541593
Nucleoside analogues have been in clinical use since 1960s and they are still used as the first therapeutic option for several cancers and viral infections, due to their high therapeutic...
5.
Garcia Gonzalez J, Hernandez F
Expert Rev Mol Diagn . 2022 Mar; 22(3):265-294. PMID: 35240900
Introduction: In the increasingly challenging field of clinical microbiology, diagnosis is a cornerstone whose accuracy and timing are crucial for the successful management, therapy, and outcome of infectious diseases. Currently...
6.
Machado I, Goikoetxea G, Alday E, Jimenez T, Arias-Moreno X, Hernandez F, et al.
Diagnostics (Basel) . 2021 Nov; 11(11). PMID: 34829369
The identification of pathogens causing infectious diseases is still based on laborious and time-consuming techniques. Therefore, there is an urgent need for the development of novel methods and devices that...
7.
Balian A, Hernandez F
Biomark Res . 2021 Nov; 9(1):86. PMID: 34809722
Early cancer diagnosis is a crucial element to improved treatment options and survival. Great research efforts have been made in the search for better performing cancer diagnostic biomarkers. However, the...
8.
Periyathambi P, Balian A, Hu Z, Padro D, Hernandez L, Uvdal K, et al.
Anal Bioanal Chem . 2021 Oct; 413(30):7353-7362. PMID: 34704109
Activatable fluorescent probes have been successfully used as molecular tools for biomedical research in the last decades. Fluorescent probes allow the detection of molecular events, providing an extraordinary platform for...
9.
Jimenez T, Botero J, Otaegui D, Calvo J, Hernandez F, San Sebastian E
J Med Chem . 2021 Aug; 64(17):12855-12864. PMID: 34460263
An undecamer oligonucleotide probe based on a pair of deoxythymidines flanked by several modified nucleotides is a specific and highly efficient biosensor for micrococcal nuclease (MNase), an endonuclease produced by...
10.
Hernandez L, Arauzo-Bravo M, Gerovska D, Solaun R, Machado I, Balian A, et al.
Cancers (Basel) . 2021 Jan; 13(2). PMID: 33451046
Breast cancer is one of the most common pathologies diagnosed in the clinical practice. Despite major advancements in diagnostic approaches, there is no widely accepted biomarker in the clinical practice...