Frank H Hezemans
Overview
Explore the profile of Frank H Hezemans including associated specialties, affiliations and a list of published articles.
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Articles
18
Citations
296
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Recent Articles
1.
Orlando I, Hezemans F, Ye R, Murley A, Holland N, Regenthal R, et al.
Brain Commun
. 2024 Oct;
6(5):fcae297.
PMID: 39464213
Noradrenaline is a powerful modulator of cognitive processes, including action decisions underlying saccadic control. Changes in saccadic eye movements are common across neurodegenerative diseases of ageing, including Parkinson's disease. With...
2.
Sacu S, Dubois M, Hezemans F, Aggensteiner P, Monninger M, Brandeis D, et al.
Biol Psychiatry
. 2024 Apr;
96(12):948-958.
PMID: 38636886
Background: Early adverse experiences are assumed to affect fundamental processes of reward learning and decision making. However, computational neuroimaging studies investigating these circuits in the context of adversity are sparse...
3.
Ye R, Hezemans F, OCallaghan C, Tsvetanov K, Rua C, Jones P, et al.
J Neurosci
. 2023 Sep;
43(42):7028-7040.
PMID: 37669861
Parkinson's disease (PD) and progressive supranuclear palsy (PSP) both impair response inhibition, exacerbating impulsivity. Inhibitory control deficits vary across individuals and are linked with worse prognosis, and lack improvement on...
4.
van den Bosch R, Hezemans F, Maatta J, Hofmans L, Papadopetraki D, Verkes R, et al.
Elife
. 2023 Apr;
12.
PMID: 37083626
Individual differences in striatal dopamine synthesis capacity have been associated with working memory capacity, trait impulsivity, and spontaneous eye-blink rate (sEBR), as measured with readily available and easily administered, 'off-the-shelf'...
5.
Malpetti M, Cope T, Street D, Jones P, Hezemans F, Mak E, et al.
Brain
. 2023 Mar;
146(8):3221-3231.
PMID: 36883644
Frontotemporal dementia is clinically and neuropathologically heterogeneous, but neuroinflammation, atrophy and cognitive impairment occur in all of its principal syndromes. Across the clinical spectrum of frontotemporal dementia, we assess the...
6.
Swaddiwudhipong N, Whiteside D, Hezemans F, Street D, Rowe J, Rittman T
Alzheimers Dement
. 2022 Oct;
19(5):1752-1763.
PMID: 36223793
Introduction: The pathophysiological processes of neurodegenerative diseases begin years before diagnosis. However, pre-diagnostic changes in cognition and physical function are poorly understood, especially in sporadic neurodegenerative disease. Methods: UK Biobank...
7.
Ye R, OCallaghan C, Rua C, Hezemans F, Holland N, Malpetti M, et al.
Mov Disord
. 2022 May;
37(8):1663-1672.
PMID: 35576973
Background: Neurodegeneration in the locus coeruleus (LC) contributes to neuropsychiatric symptoms in both Parkinson's disease (PD) and progressive supranuclear palsy (PSP). Spatial precision of LC imaging is improved with ultrahigh...
8.
Wolpe N, Hezemans F, Rae C, Zhang J, Rowe J
Cortex
. 2022 May;
152:98-108.
PMID: 35550936
The pre-supplementary motor area (pre-SMA) is central for the initiation and inhibition of voluntary action. For the execution of action, the pre-SMA optimises the decision of which action to choose...
9.
Hezemans F, Wolpe N, OCallaghan C, Ye R, Rua C, Jones P, et al.
PLoS Comput Biol
. 2022 May;
18(5):e1010079.
PMID: 35533200
Apathy is a debilitating feature of many neuropsychiatric diseases, that is typically described as a reduction of goal-directed behaviour. Despite its prevalence and prognostic importance, the mechanisms underlying apathy remain...
10.
Tomassini A, Hezemans F, Ye R, Tsvetanov K, Wolpe N, Rowe J
J Neurosci
. 2022 Mar;
42(16):3484-3493.
PMID: 35277392
Response inhibition is a core executive function enabling adaptive behavior in dynamic environments. Human and animal models indicate that inhibitory control and control networks are modulated by noradrenaline, arising from...