Frank de Gruijl
Overview
Explore the profile of Frank de Gruijl including associated specialties, affiliations and a list of published articles.
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11
Citations
80
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Recent Articles
1.
Wu S, Rietveld M, Hogervorst M, de Gruijl F, van der Burg S, Vermeer M, et al.
Int J Mol Sci
. 2022 Oct;
23(19).
PMID: 36232952
Human dermis can be morphologically divided into the upper papillary and lower reticular dermis. Previously, we demonstrated that papillary (PFs) and reticular (RFs) fibroblasts show distinct morphology and gene expression...
2.
Hogervorst M, Rietveld M, de Gruijl F, El Ghalbzouri A
Br J Cancer
. 2018 Mar;
118(8):1089-1097.
PMID: 29551776
Background: Tumour stroma consists of a heterogeneous population of fibroblasts and related mesenchymal cells, collectively dubbed cancer-associated fibroblasts (CAFs). These CAFs are key players in cancer invasion of cutaneous squamous...
3.
Miller S, Coelho S, Yamaguchi Y, Hearing V, Beer J, de Gruijl F
Photochem Photobiol
. 2017 Apr;
93(5):1282-1288.
PMID: 28380699
Erythema (i.e. visible redness) and DNA damage caused by ultraviolet radiation (UVR) in human skin have similar action spectra and show good correlation after a single exposure to UVR. We...
4.
5.
van de Glind G, Rebel H, van Kempen M, Tensen K, de Gruijl F
Oncotarget
. 2016 Jan;
7(7):8067-77.
PMID: 26797757
Sunburns and especially sub-sunburn chronic UV exposure are associated with increased risk of squamous cell carcinomas (SCCs). Here we focus on a possible difference in tumor initiation from a single...
6.
van Doorn R, de Gruijl F
J Invest Dermatol
. 2015 Nov;
135(12):2911-2913.
PMID: 26569583
The migration of dermal mast cells to skin-draining lymph nodes is a key step in UV-induced immunosuppression. Examining the effects of platelet-activating factor (PAF), a phospholipid mediator secreted by keratinocytes...
7.
Xiang F, Lucas R, de Gruijl F, Norval M
Photochem Photobiol Sci
. 2015 Nov;
14(12):2138-46.
PMID: 26548800
Defining whether skin pigmentation influences vitamin D photosynthesis is important for delivering accurate public health messages. Current evidence is contradictory. We undertook a systematic review of the published literature to...
8.
Fotouhi A, Hagos W, Ilic M, Wojcik A, Harms-Ringdahl M, de Gruijl F, et al.
Mutat Res
. 2013 Oct;
751-752:8-14.
PMID: 24144844
Ultraviolet radiation is a highly mutagenic agent that damages the DNA by the formation of mutagenic photoproducts at dipyrimidine sites and by oxidative DNA damages via reactive oxygen species (ROS)....
9.
de Gruijl F
J Invest Dermatol
. 2009 Jul;
129(8):1853-6.
PMID: 19603051
UV-induced apoptosis, giving rise to "sunburn cells," has been thought to be primarily cell autonomous (or intrinsic) in nature, triggered by DNA damage and mediated through p53. However, in vivo...
10.
Janssens A, Pavel S, Ling T, Winhoven S, Anastasopoulou N, Stratigos A, et al.
Arch Dermatol
. 2007 May;
143(5):599-604.
PMID: 17515509
Objective: To examine whether the ease of disease provocation by UV-A and/or UV-B radiation correlates with clinical features of polymorphic light eruption (PLE), including those indicative of disease severity. Design:...