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Frank C T van der Heide

Explore the profile of Frank C T van der Heide including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Mokhtar S, Viljoen J, van der Kallen C, Berendschot T, Dagnelie P, Albers J, et al.
Environ Health . 2024 Sep; 23(1):70. PMID: 39232744
Background: Epidemiological and toxicological studies indicate that increased exposure to air pollutants can lead to neurodegenerative diseases. To further confirm this relationship, we evaluated the association between exposure to ambient...
2.
Danilevicz I, van Hees V, van der Heide F, Jacob L, Landre B, Benadjaoud M, et al.
BMC Med Res Methodol . 2024 Jun; 24(1):132. PMID: 38849718
Accelerometers, devices that measure body movements, have become valuable tools for studying the fragmentation of rest-activity patterns, a core circadian rhythm dimension, using metrics such as inter-daily stability (IS), intradaily...
3.
Weerts J, Raafs A, Sandhoefner B, van der Heide F, Mourmans S, Wolff N, et al.
J Clin Med . 2024 Apr; 13(7). PMID: 38610657
Systemic microvascular regression and dysfunction are considered important underlying mechanisms in heart failure with preserved ejection fraction (HFpEF), but retinal changes are unknown. This prospective study aimed to investigate whether...
4.
van der Heide F, Valeri L, Dugravot A, Danilevicz I, Landre B, Kivimaki M, et al.
EClinicalMedicine . 2024 Mar; 70:102539. PMID: 38516105
Background: The contribution of modifiable risk factors to social inequalities in dementia, observed in longitudinal studies, remains unclear. We aimed to quantify the role of cardiovascular health factors, assessed using...
5.
van der Heide F, Steens I, Limmen B, Mokhtar S, van Boxtel M, Schram M, et al.
Alzheimers Dement . 2023 Aug; 20(1):316-329. PMID: 37611119
Introduction: The retina may provide non-invasive, scalable biomarkers for monitoring cerebral neurodegeneration. Methods: We used cross-sectional data from The Maastricht study (n = 3436; mean age 59.3 years; 48% men;...
6.
Mokhtar S, van der Heide F, Oyaert K, van der Kallen C, Berendschot T, Scarpa F, et al.
Diabetologia . 2023 Aug; 66(11):2030-2041. PMID: 37589735
Aims/hypothesis: To assess the associations between glucose metabolism status and a range of continuous measures of glycaemia with corneal nerve fibre measures, as assessed using corneal confocal microscopy. Methods: We...
7.
van der Heide F, Khawaja A, Berendschot T, Littlejohns T, Kuzma E, Luben R, et al.
Alzheimers Dement . 2023 Aug; 20(1):211-220. PMID: 37551793
Introduction: Our main objective was to investigate whether retinal neurodegeneration, estimated from lower thickness of inner retinal layers, was associated with incident all-cause dementia and Alzheimer's disease (AD). Methods: We...
8.
van der Heide F, Mokhtar S, Khanna A, Said M, Henry R, Kroon A, et al.
J Alzheimers Dis . 2023 May; 93(4):1471-1483. PMID: 37182886
Background: If retinal indices of neurodegeneration are to be biomarkers for the monitoring of cerebral neurodegeneration, it is important to establish whether potentially modifiable risk factors for dementia are associated...
9.
van der Heide F, Eussen S, Houben A, Henry R, Kroon A, van der Kallen C, et al.
Cardiovasc Diabetol . 2023 Mar; 22(1):67. PMID: 36964536
Background: Microvascular dysfunction (MVD) is an important contributor to major clinical disease such as stroke, dementia, depression, retinopathy, and chronic kidney disease. Alcohol consumption may be a determinant of MVD....
10.
van der Heide F, van Sloten T, Willekens N, Stehouwer C
Front Endocrinol (Lausanne) . 2022 Dec; 13:1014287. PMID: 36506058
Dysfunction of the neurovascular coupling unit may be an important contributor to dementia. The neurovascular coupling unit comprises neuronal structures (e.g. astrocytes) and vascular structures (e.g. endothelial cells) that functionally...