Francoise Silvy
Overview
Explore the profile of Francoise Silvy including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
18
Citations
274
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0
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Recent Articles
1.
Mohamed Abd-El-Halim Y, El Kaoutari A, Silvy F, Rubis M, Bigonnet M, Roques J, et al.
EBioMedicine
. 2021 Aug;
71:103541.
PMID: 34425307
Background: Pancreatic ductal adenocarcinoma (PDAC) is characterized by an important heterogeneity, reflected by different clinical outcomes and chemoresistance. During carcinogenesis, tumor cells display aberrant glycosylated structures, synthetized by deregulated glycosyltransferases,...
2.
Siret C, Collignon A, Silvy F, Robert S, Cheyrol T, Andre P, et al.
Front Immunol
. 2020 Feb;
10:3070.
PMID: 32038621
Pancreatic ductal adenocarcinoma (PDAC) is a fatal disease with rising incidence and a remarkable resistance to current therapies. The reasons for this therapeutic failure include the tumor's extensive infiltration by...
3.
Swayden M, Alzeeb G, Masoud R, Berthois Y, Audebert S, Camoin L, et al.
FASEB J
. 2019 Sep;
33(11):12447-12463.
PMID: 31557059
The dismal prognosis of pancreatic ductal adenocarcinoma (PDAC) is mainly due to its rapidly acquired resistance to all conventional treatments. Despite drug-specific mechanisms of resistance, none explains how these cells...
4.
Boudouresque F, Siret C, Dobric A, Silvy F, Soubeyran P, Iovanna J, et al.
Oncotarget
. 2018 Dec;
9(89):35941-35961.
PMID: 30542509
The microRNA-200 (miR-200) family is frequently down-regulated in tumors, including pancreatic adenocarcinomas (PDACs). In this study we have examined the mechanisms involved in the loss of miR-200s in tumoral pancreatic...
5.
Collignon A, Silvy F, Robert S, Trad M, Germain S, Nigri J, et al.
Oncoimmunology
. 2018 Dec;
7(12):e1504727.
PMID: 30524902
Pancreatic adenocarcinoma (PAC) has a poor prognosis. One treatment approach, investigated here, is to reinforce antitumor immunity. Dendritic cells (DCs) are essential for the development and regulation of adaptive host...
6.
Lombardo D, Silvy F, Crenon I, Martinez E, Collignon A, Beraud E, et al.
Oncotarget
. 2018 Mar;
9(15):12513-12533.
PMID: 29552330
Pancreatic adenocarcinomas and diabetes mellitus are responsible for the deaths of around two million people each year worldwide. Patients with chronic pancreatitis do not die directly of this disease, except...
7.
Terciolo C, Dobric A, Ouaissi M, Siret C, Breuzard G, Silvy F, et al.
J Crohns Colitis
. 2017 Mar;
11(8):999-1010.
PMID: 28333335
Background And Aims: Alteration in intestinal permeability is the main factor underlying the pathogenesis of many diseases affecting the gut, such as inflammatory bowel disease [IBD]. Characterization of molecules targeting...
8.
Martinez E, Crenon I, Silvy F, Del Grande J, Mougel A, Barea D, et al.
Oncotarget
. 2016 Sep;
8(1):536-551.
PMID: 27602750
Pancreatic adenocarcinoma (PDAC) is a dismal disease. The lack of specific symptoms still leads to a delay in diagnosis followed by death within months for most patients. Exon 11 of...
9.
Martinez E, Silvy F, Fina F, Bartoli M, Krahn M, Barlesi F, et al.
Oncotarget
. 2015 Oct;
6(37):39855-64.
PMID: 26498142
Pancreatic cancer (PC) is a devastating disease progressing asymptomatically until death within months after diagnosis. Defining at-risk populations should promote its earlier diagnosis and hence also avoid its development. Considering...
10.
Collignon A, Perles-Barbacaru A, Robert S, Silvy F, Martinez E, Crenon I, et al.
Oncotarget
. 2015 Sep;
6(27):23462-79.
PMID: 26405163
Oncofetal fucose-rich glycovariants of the pathological bile salt-dependent lipase (pBSDL) appear during human pancreatic oncogenesis and are detected by themonoclonal antibody J28 (mAbJ28). We aimed to identify murine counterparts onpancreatic...