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Francoise Grelac

Explore the profile of Francoise Grelac including associated specialties, affiliations and a list of published articles. Areas
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Articles 8
Citations 119
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Recent Articles
1.
Bouvard C, Galy-Fauroux I, Grelac F, Carpentier W, Lokajczyk A, Gandrille S, et al.
Mar Drugs . 2015 Dec; 13(12):7446-62. PMID: 26694425
Low-molecular-weight fucoidan (LMWF) is a sulfated polysaccharide extracted from brown seaweed that presents antithrombotic and pro-angiogenic properties. However, its mechanism of action is not well-characterized. Here, we studied the effects...
2.
Benslimane-Ahmim Z, Poirier F, Delomenie C, Lokajczyk A, Grelac F, Galy-Fauroux I, et al.
Angiogenesis . 2013 Feb; 16(3):575-93. PMID: 23386104
Osteoprotegerin (OPG), a soluble tumour necrosis factor receptor superfamily member, inhibits RANKL-mediated osteoclastogenesis. We have previously reported that OPG enhances the proangiogenic properties of endothelial colony-forming cells (ECFCs) in vitro,...
3.
Dias J, Benslimane-Ahmim Z, Egot M, Lokajczyk A, Grelac F, Galy-Fauroux I, et al.
Biochem Pharmacol . 2012 Jul; 84(8):1014-23. PMID: 22796565
Thrombospondin-1 (TSP-1) gives rise to fragments that have both pro- and anti-angiogenic effects in vitro and in vivo. The TSP-HepI peptide (2.3 kDa), located in the N-terminal domain of TSP-1,...
4.
Smadja D, dAudigier C, Weiswald L, Badoual C, Dangles-Marie V, Mauge L, et al.
Arterioscler Thromb Vasc Biol . 2010 Sep; 30(12):2544-52. PMID: 20847303
Objective: To determine the role of Wnt antagonist Dickkopf (DKK) 1 in human endothelial colony-forming cells (ECFCs) in view of the emerging importance of Wnt pathways in vascular biology. Methods...
5.
Hindy-Francois C, Bachelot-Loza C, Le Bonniec B, Grelac F, Dizier B, Godier A, et al.
Thromb Haemost . 2010 Jul; 104(4):823-30. PMID: 20664889
Combined antiplatelet agents (cAPA), aspirin plus clopidogrel, increase the risk of bleeding. We hypothesised that recombinant activated FVIIa (rFVIIa), which normalises thrombin generation in platelet-rich plasma from patients treated with...
6.
Lasne D, Baujat G, Mirault T, Lunardi J, Grelac F, Egot M, et al.
Br J Haematol . 2010 Jul; 150(6):685-8. PMID: 20629659
Lowe syndrome (LS) is a rare X-linked disorder caused by mutations in the oculocerebrorenal gene (OCRL), encoding OCRL, a phosphatidylinositol 5-phosphatase with a RhoGAP domain. An abnormal rate of haemorrhagic...
7.
Smadja D, Bieche I, Susen S, Mauge L, Laurendeau I, dAudigier C, et al.
J Cell Mol Med . 2008 Jul; 13(8B):2534-2546. PMID: 18657231
The proinflammatory chemokine interleukin 8 exerts potent angiogenic effects on endothelial cells by interacting with its receptors CXCR1 and CXCR2. As thrombin is also a potent inflammatory factor, and as...
8.
Bourgeois S, Rossignol P, Grelac F, Chalumeau C, Klein C, Laghmani K, et al.
Pflugers Arch . 2003 Jul; 446(6):672-83. PMID: 12836026
Studying the apical Na/H exchanger NHE2 is difficult in the intact thick ascending limb (TAL) because of its weak expression and transport activity compared with the co-expressed NHE3. From a...