Francois Hermetet
Overview
Explore the profile of Francois Hermetet including associated specialties, affiliations and a list of published articles.
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Articles
23
Citations
281
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0
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Recent Articles
11.
Delmas D, Hermetet F, Aires V
Cancers (Basel)
. 2021 Sep;
13(18).
PMID: 34572736
Immune checkpoints refer to a range of immunoregulatory molecules that modulate the immune response. For example, proteins expressed at the surface of T-cells (including PD-1 and CTLA-4) and their ligands...
12.
Dias A, Douhard R, Hermetet F, Regimbeau M, Lopez T, Gonzalez D, et al.
J Gastroenterol
. 2021 Mar;
56(5):442-455.
PMID: 33782752
Background: We previously showed that supernatants of Lactobacillus biofilms induced an anti-inflammatory response by affecting the secretion of macrophage-derived cytokines, which was abrogated upon immunodepletion of the stress protein GroEL....
13.
Marcion G, Hermetet F, Neiers F, Uyanik B, Dondaine L, Dias A, et al.
Int J Cancer
. 2021 Jan;
148(12):3019-3031.
PMID: 33506516
The presence of an inactivating heat shock protein 110 (HSP110) mutation in colorectal cancers has been correlated with an excellent prognosis and with the ability of HSP110 to favor the...
14.
Hermetet F, Mshaik R, Simonet J, Callier P, Delva L, Quere R
Sci Rep
. 2020 Oct;
10(1):16187.
PMID: 32999332
Using a MLL-AF9 knock-in mouse model, we discovered that consumption of a high-fat diet (HFD) accelerates the risk of developing acute myeloid leukemia (AML). This regimen increases the clusterization of...
15.
De Almeida S, Regimbeau M, Jego G, Garrido C, Girodon F, Hermetet F
Cancers (Basel)
. 2020 Sep;
12(9).
PMID: 32932806
Myeloproliferative neoplasms (MPN) are a group of clonal disorders that affect hematopoietic stem/progenitor cells. These disorders are often caused by oncogenic driver mutations associated with persistent Janus kinase (JAK)/signal transducer...
16.
Jego G, Hermetet F, Girodon F, Garrido C
Cancers (Basel)
. 2019 Dec;
12(1).
PMID: 31861612
While cells from multicellular organisms are dependent upon exogenous signals for their survival, growth, and proliferation, commitment to a specific cell fate requires the correct folding and maturation of proteins,...
17.
Buffiere A, Uzan B, Aucagne R, Hermetet F, Mas M, Nassurdine S, et al.
Oncogene
. 2019 Aug;
38(48):7357-7365.
PMID: 31417180
T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive hematological malignancy characterized by an accumulation of immature T cells. Although patient outcomes have improved, novel targeted therapies are needed to reduce...
18.
Gozzi G, Gonzalez D, Boudesco C, Dias A, Gotthard G, Uyanik B, et al.
Cell Death Differ
. 2019 May;
27(1):117-129.
PMID: 31068676
Pro-survival stress-inducible chaperone HSP110 is the only HSP for which a mutation has been found in a cancer. Multicenter clinical studies demonstrated a direct association between HSP110 inactivating mutation presence...
19.
Hermetet F, Buffiere A, Aznague A, Pais de Barros J, Bastie J, Delva L, et al.
Nat Commun
. 2019 Feb;
10(1):523.
PMID: 30705272
Despite recent in vivo data demonstrating that high-fat diet (HFD)-induced obesity leads to major perturbations in murine hematopoietic stem cells (HSC), the direct role of a HFD is not yet...
20.
Guenat D, Hermetet F, Pretet J, Mougin C
Viruses
. 2017 Aug;
9(8).
PMID: 28783104
Extracellular vesicles (EVs), including exosomes (Exos), microvesicles (MVs) and apoptotic bodies (ABs) are released in biofluids by virtually all living cells. Tumor-derived Exos and MVs are garnering increasing attention because...