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Francois Gueyffier

Explore the profile of Francois Gueyffier including associated specialties, affiliations and a list of published articles. Areas
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Articles 164
Citations 2395
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Recent Articles
1.
Gougeon A, Granal M, Granal M, Massy E, Massy E, Gueyffier F, et al.
Joint Bone Spine . 2025 Feb; :105871. PMID: 40015362
Objectives: Bisphosphonates are widely used to treat osteoporosis, bone cancer, Paget's disease, and hypercalcemia to reduce fracture risk. Observational studies have highlighted rare but serious adverse events (AE). Some meta-analyses...
2.
Hure J, Foucault L, Ghayad L, Marie C, Vachoud N, Baudouin L, et al.
Nat Commun . 2025 Jan; 16(1):538. PMID: 39788999
No abstract available.
3.
Hure J, Foucault L, Ghayad L, Marie C, Vachoud N, Baudouin L, et al.
Nat Commun . 2024 Nov; 15(1):9837. PMID: 39537633
Oligodendrocytes are critical for CNS myelin formation and are involved in preterm-birth brain injury (PBI) and multiple sclerosis (MS), both of which lack effective treatments. We present a pharmacogenomic approach...
4.
Esparragosa Vazquez I, Sanson M, Chinot O, Fontanilles M, Rivoirard R, Thomas-Maisonneuve L, et al.
Neurooncol Adv . 2024 Jun; 6(1):vdae078. PMID: 38855053
Background: Based on preclinical studies showing that IDH-mutant (IDHm) gliomas could be vulnerable to PARP inhibition we launched a multicenter phase 2 study to test the efficacy of olaparib monotherapy...
5.
Bouvier F, Chaimani A, Peyrot E, Gueyffier F, Grenet G, Porcher R
BMC Med Res Methodol . 2024 Mar; 24(1):74. PMID: 38528447
Background: One key aspect of personalized medicine is to identify individuals who benefit from an intervention. Some approaches have been developed to estimate individualized treatment effects (ITE) with a single...
6.
Seron C, Olivero P, Flores N, Cruzat B, Ahumada F, Gueyffier F, et al.
Front Public Health . 2024 Jan; 11:1270557. PMID: 38192555
Type 2 diabetes and its associated cardiovascular risk is an escalating epidemic that represents a significant public health burden due to increased morbidity and mortality, disproportionately affecting disadvantaged communities. Poor...
7.
Vacheron C, Lepape A, Venet F, Monneret G, Gueyffier F, Boutitie F, et al.
J Crit Care . 2023 Jun; 78:154330. PMID: 37267804
Purpose: Septic shock is associated in some patients with a profound immunosuppression. We hypothesized that GM-CSF would reduce the occurrence of ICU-acquired infections in immunosuppressed septic patients. Methods: Randomized double-blind...
8.
Fall M, Grenet G, Le H, Kassai B, Lega J, Boussageon R, et al.
Therapie . 2023 Feb; 78(6):667-678. PMID: 36841655
Background: The polypill strategy could become widely accepted in cardiovascular prevention due to reduced costs and its simplicity, which promote compliance. Aspirin is often included as a component of the...
9.
Vanier A, Fernandez J, Kelley S, Alter L, Semenzato P, Alberti C, et al.
BMJ Evid Based Med . 2023 Feb; 29(1):1-5. PMID: 36788020
No abstract available.
10.
Meunier P, Raynaud C, Guimaraes E, Gueyffier F, Letrilliart L
Ann Fam Med . 2023 Jan; 21(1):57-69. PMID: 36690490
Purpose: To identify and quantify the barriers and facilitators to the use of clinical decision support systems (CDSSs) by primary care professionals (PCPs). Methods: A mixed-methods systematic review was conducted...