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Francois Cornet

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Citations 984
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Recent Articles
11.
Crozat E, Tardin C, Salhi M, Rousseau P, Lablaine A, Bertoni T, et al.
Nat Commun . 2020 Aug; 11(1):3796. PMID: 32732900
The ter region of the bacterial chromosome, where replication terminates, is the last to be segregated before cell division in Escherichia coli. Delayed segregation is controlled by the MatP protein,...
12.
Planchenault C, Pons M, Schiavon C, Siguier P, Rech J, Guynet C, et al.
J Mol Biol . 2020 Jan; 432(3):745-761. PMID: 31931015
Bacterial genomes, organized intracellularly as nucleoids, are composed of the main chromosome coexisting with different types of secondary replicons. Secondary replicons are major drivers of bacterial adaptation by gene exchange....
13.
Campos M, Govers S, Irnov I, Dobihal G, Cornet F, Jacobs-Wagner C
Mol Syst Biol . 2018 Jun; 14(6):e7573. PMID: 29941428
Cell size, cell growth, and cell cycle events are necessarily intertwined to achieve robust bacterial replication. Yet, a comprehensive and integrated view of these fundamental processes is lacking. Here, we...
14.
Fournes F, Crozat E, Pages C, Tardin C, Salome L, Cornet F, et al.
Proc Natl Acad Sci U S A . 2016 Jun; 113(28):7882-7. PMID: 27317749
In bacteria, the FtsK/Xer/dif (chromosome dimer resolution site) system is essential for faithful vertical genetic transmission, ensuring the resolution of chromosome dimers during their segregation to daughter cells. This system...
15.
El Sayyed H, Le Chat L, Lebailly E, Vickridge E, Pages C, Cornet F, et al.
PLoS Genet . 2016 May; 12(5):e1006025. PMID: 27171414
Catenation links between sister chromatids are formed progressively during DNA replication and are involved in the establishment of sister chromatid cohesion. Topo IV is a bacterial type II topoisomerase involved...
16.
Crozat E, Fournes F, Cornet F, Hallet B, Rousseau P
Microbiol Spectr . 2015 Jun; 2(5). PMID: 26104344
One of the disadvantages of circular plasmids and chromosomes is their high sensitivity to rearrangements caused by homologous recombination. Odd numbers of crossing-over occurring during or after replication of a...
17.
Crozat E, Rousseau P, Fournes F, Cornet F
J Mol Microbiol Biotechnol . 2015 Mar; 24(5-6):396-408. PMID: 25732341
A global view of bacterial chromosome choreography during the cell cycle is emerging, highlighting as a next challenge the description of the molecular mechanisms and factors involved. Here, we review...
18.
Bouet J, Stouf M, Lebailly E, Cornet F
Curr Opin Microbiol . 2014 Dec; 22:60-5. PMID: 25460797
Bacteria face the problem of segregating their gigantic chromosomes without a segregation period restricted in time and space, as Eukaryotes do. Segregation thus involves multiple activities, general or specific of...
19.
Diagne C, Salhi M, Crozat E, Salome L, Cornet F, Rousseau P, et al.
Nucleic Acids Res . 2013 Nov; 42(3):1721-32. PMID: 24214995
Circular chromosomes can form dimers during replication and failure to resolve those into monomers prevents chromosome segregation, which leads to cell death. Dimer resolution is catalysed by a highly conserved...
20.
Stouf M, Meile J, Cornet F
Proc Natl Acad Sci U S A . 2013 Jun; 110(27):11157-62. PMID: 23781109
Bacteria use the replication origin-to-terminus polarity of their circular chromosomes to control DNA transactions during the cell cycle. Segregation starts by active migration of the region of origin followed by...