Francis C Edozie
Overview
Explore the profile of Francis C Edozie including associated specialties, affiliations and a list of published articles.
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5
Citations
247
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Recent Articles
1.
Edozie F, Nova-Lamperti E, Povoleri G, Scotta C, John S, Lombardi G, et al.
Transplantation
. 2014 Jun;
98(4):370-9.
PMID: 24933458
Clinical tolerance induction to permit minimization or cessation of immunosuppressive drugs is one of the key research goals in solid organ transplantation. The use of ex vivo expanded or manipulated...
2.
Afzali B, Mitchell P, Edozie F, Povoleri G, Dowson S, Demandt L, et al.
Eur J Immunol
. 2013 May;
43(8):2043-54.
PMID: 23677517
Treg cells are critical for the prevention of autoimmune diseases and are thus prime candidates for cell-based clinical therapy. However, human Treg cells are "plastic", and are able to produce...
3.
Afzali B, Edozie F, Fazekasova H, Scotta C, Mitchell P, Canavan J, et al.
Clin J Am Soc Nephrol
. 2013 Apr;
8(8):1396-405.
PMID: 23580782
Background And Objectives: Cell-based therapy with natural (CD4(+)CD25(hi)CD127(lo)) regulatory T cells to induce transplant tolerance is now technically feasible. However, regulatory T cells from hemodialysis patients awaiting transplantation may be...
4.
Scotta C, Esposito M, Fazekasova H, Fanelli G, Edozie F, Ali N, et al.
Haematologica
. 2012 Dec;
98(8):1291-9.
PMID: 23242600
Adoptive transfer of ex vivo expanded CD4(+)CD25(+)FOXP3(+) regulatory T cells is a successful therapy for autoimmune diseases and transplant rejection in experimental models. In man, equivalent manipulations in bone marrow...
5.
Canavan J, Afzali B, Scotta C, Fazekasova H, Edozie F, Macdonald T, et al.
Blood
. 2012 Jan;
119(8):e57-66.
PMID: 22219224
Regulatory T cells (CD4(+)CD25(hi)CD127(lo)FOXP3(+) T cells [Tregs]) are a population of lymphocytes involved in the maintenance of self-tolerance. Abnormalities in function or number of Tregs are a feature of autoimmune...