Francis Berthias
Overview
Explore the profile of Francis Berthias including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
41
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Recent Articles
1.
Thurman H, Wijegunawardena G, Berthias F, Williamson D, Wu H, Nagy G, et al.
Anal Chem
. 2024 Feb;
96(6):2318-2326.
PMID: 38301112
Ion mobility spectrometry (IMS) coupled to mass spectrometry (MS) has become a versatile tool to fractionate complex mixtures, distinguish structural isomers, and elucidate molecular geometries. Along with the whole MS...
2.
Berthias F, Bilgin N, Mecinovic J, Jensen O
Proteomics
. 2024 Jan;
24(3-4):e2200471.
PMID: 38282202
Enzymatic catalysis is one of the fundamental processes that drives the dynamic landscape of post-translational modifications (PTMs), expanding the structural and functional diversity of proteins. Here, we assessed enzyme specificity...
3.
Berthias F, Cooper-Shepherd D, Holck F, Langridge J, Jensen O
Anal Chem
. 2023 Jul;
95(29):11141-11148.
PMID: 37434406
Unambiguous identification of distinct proteoforms and their biological functions is a significant analytical challenge due to the many combinations of post-translational modifications (PTM) that generate isomeric proteoforms. Resulting chimeric tandem...
4.
Berthias F, Thurman H, Wijegunawardena G, Wu H, Shvartsburg A, Jensen O
Anal Chem
. 2022 Dec;
95(2):784-791.
PMID: 36562749
Continuing advances in proteomics highlight the ubiquity and biological importance of proteoforms─proteins with varied sequence, splicing, or distribution of post-translational modifications (PTMs). The preeminent example is histones, where the PTM...
5.
Alhajji E, Boulghobra A, Bonose M, Berthias F, Moussa F, Maitre P
Anal Chem
. 2022 Sep;
94(37):12578-12585.
PMID: 36074025
Despite recent technological developments in analytical chemistry, separation and direct characterization of transient intermediates remain an analytical challenge. Among these, separation and direct characterization of quinonoid dihydrobiopterin (qH2Bip), a transient...
6.
Berthias F, Poad B, Thurman H, Bowman A, Blanksby S, Shvartsburg A
J Am Soc Mass Spectrom
. 2021 Nov;
32(12):2827-2836.
PMID: 34751570
The preponderance and functional importance of isomeric biomolecules have become topical in biochemistry. Therefore, one must distinguish and identify all such forms across compound classes, over a wide dynamic range...
7.
Berthias F, Baird M, Shvartsburg A
Anal Chem
. 2021 Feb;
93(8):4015-4022.
PMID: 33587599
Life was originally assumed to utilize the l-amino acids only. Since 1980s, the d-amino acid-containing peptides (DAACPs) were detected in animals, often at extremely low levels with tremendous functional specificity....
8.
Berthias F, Wang Y, Alhajji E, Rieul B, Moussa F, Benoist J, et al.
Analyst
. 2020 Jun;
145(14):4889-4900.
PMID: 32478762
Amino acids and related compounds constitute a class of biomarkers which is analyzed for early diagnosis of metabolic diseases (MDs). Protocols based on liquid chromatography hyphenated to tandem mass spectrometry...
9.
Berthias F, Maatoug B, Glish G, Moussa F, Maitre P
J Am Soc Mass Spectrom
. 2018 Feb;
29(4):752-760.
PMID: 29468501
Due to their central role in biochemical processes, fast separation and identification of amino acids (AA) is of importance in many areas of the biomedical field including the diagnosis and...
10.
Lesslie M, Yang Y, Canty A, Piacentino E, Berthias F, Maitre P, et al.
Chem Commun (Camb)
. 2017 Dec;
54(4):346-349.
PMID: 29226932
A new decarbonylation reaction is observed for [(K-acetate)Pd(K-diphosphine)] complexes. Gas-phase IR experiments identify the product as [CHPd(OP(Ph)CHPPh)]. DFT calculations uncovered a plausible mechanism involving O atom abstraction by the diphosphine...