Francijna E van den Hil
Overview
Explore the profile of Francijna E van den Hil including associated specialties, affiliations and a list of published articles.
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17
Citations
470
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Recent Articles
1.
Arslan U, van den Hil F, Mummery C, Orlova V
Curr Protoc
. 2024 Jul;
4(7):e1097.
PMID: 39036931
In the heart in vivo, vasculature forms a semi-permeable endothelial barrier for selective nutrient and (immune) cell delivery to the myocardium and removal of waste products. Crosstalk between the vasculature...
2.
Nahon D, Vila Cuenca M, van den Hil F, Hu M, de Korte T, Frimat J, et al.
Stem Cell Reports
. 2024 Jun;
19(7):946-956.
PMID: 38876110
Functionality of the blood-brain barrier (BBB) relies on the interaction between endothelial cells (ECs), pericytes, and astrocytes to regulate molecule transport within the central nervous system. Most experimental models for...
3.
Maulana T, Teufel C, Cipriano M, Roosz J, Lazarevski L, van den Hil F, et al.
Cell Stem Cell
. 2024 May;
31(7):989-1002.e9.
PMID: 38754430
Physiologically relevant human models that recapitulate the challenges of solid tumors and the tumor microenvironment (TME) are highly desired in the chimeric antigen receptor (CAR)-T cell field. We developed a...
4.
Arslan U, Brescia M, Meraviglia V, Nahon D, van Helden R, Stein J, et al.
Stem Cell Reports
. 2023 Oct;
18(10):2003.
PMID: 37820576
No abstract available.
5.
Nahon D, Ganesh S, van den Hil F, Freund C, Mummery C, Orlova V
Stem Cell Res
. 2023 Aug;
71:103180.
PMID: 37603921
Dutch-type cerebral amyloid angiopathy (D-CAA), also known as hereditary cerebral haemorrhage with amyloidosis-Dutch type (HCHWA-D), is an autosomal dominant disorder caused by a G to C transversion in codon 693...
6.
Arslan U, Brescia M, Meraviglia V, Nahon D, van Helden R, Stein J, et al.
Stem Cell Reports
. 2023 Jun;
18(7):1394-1404.
PMID: 37390826
Functional vasculature is essential for delivering nutrients, oxygen, and cells to the heart and removing waste products. Here, we developed an in vitro vascularized human cardiac microtissue (MT) model based...
7.
Cao X, Mircea M, Yakala G, van den Hil F, Brescia M, Mei H, et al.
Stem Cells
. 2022 Dec;
41(2):140-152.
PMID: 36512477
The ability to differentiate human-induced pluripotent stem cells (hiPSCs) efficiently into defined cardiac lineages, such as cardiomyocytes and cardiac endothelial cells, is crucial to study human heart development and model...
8.
de Graaf M, Vivas A, Kasi D, van den Hil F, van den Berg A, van der Meer A, et al.
Lab Chip
. 2022 Dec;
23(1):168-181.
PMID: 36484766
Three-dimensional (3D) blood vessels-on-a-chip (VoC) models integrate the biological complexity of vessel walls with dynamic microenvironmental cues, such as wall shear stress (WSS) and circumferential strain (CS). However, these parameters...
9.
Bulut M, Vila Cuenca M, de Graaf M, van den Hil F, Mummery C, Orlova V
Curr Protoc
. 2022 Oct;
2(10):e564.
PMID: 36250774
Blood vessels are composed of endothelial cells (ECs) that form the inner vessel wall and mural cells that cover the ECs to mediate their stabilization. Crosstalk between ECs and VSMCs...
10.
Vila Cuenca M, Cochrane A, van den Hil F, de Vries A, Lesnik Oberstein S, Mummery C, et al.
Stem Cell Reports
. 2021 Sep;
16(9):2159-2168.
PMID: 34478648
Crosstalk between endothelial cells (ECs) and pericytes or vascular smooth muscle cells (VSMCs) is essential for the proper functioning of blood vessels. This balance is disrupted in several vascular diseases...