Franciele de Lima
Overview
Explore the profile of Franciele de Lima including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
128
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0
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Recent Articles
1.
Barbosa M, de Lima F, Moraes C, Borba-Junior I, Huber S, Santos I, et al.
Front Med (Lausanne)
. 2024 May;
11:1367544.
PMID: 38803346
Coagulation activation in immunothrombosis involves various pathways distinct from classical hemostasis, offering potential therapeutic targets to control inflammation-induced hypercoagulability while potentially sparing hemostasis. The Angiopoietin/Tie2 pathway, previously linked to embryonic...
2.
de Lima F, Hounkpe B, de Moraes C, Borba-Junior I, Costa F, de Paula E
Exp Biol Med (Maywood)
. 2023 Jul;
248(13):1103-1111.
PMID: 37452705
Heme is a fundamental molecule for several biological processes, but when released in the extracellular space such as in hemolytic diseases, it can be toxic to cells and tissues. Hemopexin...
3.
Moraes C, Borba-Junior I, de Lima F, Silva J, Bombassaro B, Palma A, et al.
Front Physiol
. 2023 Mar;
14:1113968.
PMID: 36895630
Endothelial barrier (EB) disruption contributes to acute lung injury in COVID-19, and levels of both VEGF-A and Ang-2, which are mediators of EB integrity, have been associated with COVID-19 severity....
4.
de Lima F, Moraes C, Barbosa M, Bombassaro B, Palma A, Dertkigil S, et al.
Exp Biol Med (Maywood)
. 2023 Feb;
248(4):309-316.
PMID: 36740756
Heme-oxygenase 1 (HO-1) is an enzyme with well-known anti-inflammatory and antioxidant properties, whose levels have been previously associated with disease severity in the context of sterile and infectious diseases. Moreover,...
5.
Cardoso E, Silva-Neto P, Hounkpe B, Chenou F, Albuquerque C, Garcia N, et al.
Hematol Oncol Stem Cell Ther
. 2021 Aug;
16(2):124-132.
PMID: 34450106
Objective/background: Sickle cell anemia (SCA) is associated with increased levels of extracellular heme, which is a key mediator of inflammation in this condition. Despite abundant evidence supporting this concept in...
6.
Santaterra V, Fiusa M, Hounkpe B, Chenou F, Tonasse W, da Costa L, et al.
Front Immunol
. 2020 Dec;
11:535147.
PMID: 33381108
Free extracellular heme has been shown to activate several compartments of innate immunity, acting as a danger-associated molecular pattern (DAMP) in hemolytic diseases. Although localized endothelial barrier (EB) disruption is...
7.
Hounkpe B, Chenou F, de Lima F, De Paula E
Nucleic Acids Res
. 2020 Jul;
49(D1):D947-D955.
PMID: 32663312
Housekeeping (HK) genes are constitutively expressed genes that are required for the maintenance of basic cellular functions. Despite their importance in the calibration of gene expression, as well as the...
8.
Campos Nogueira Y, da Costa L, Levy C, Orsi F, de Lima F, Annichinno-Bizzacchi J, et al.
PLoS One
. 2020 Jan;
14(12):e0226871.
PMID: 31891611
The biological relevance of fibrinolysis to the host response to sepsis is illustrated by pathogens such as S. pyogenes and Y. pestis, whose virulence factors are proteins that challenge the...