Francesca Massenzio
Overview
Explore the profile of Francesca Massenzio including associated specialties, affiliations and a list of published articles.
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Articles
30
Citations
508
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Recent Articles
1.
Fazzina M, Bergonzoni M, Massenzio F, Monti B, Frabetti F, Casadei R
Sci Rep
. 2025 Jan;
15(1):3561.
PMID: 39875457
No abstract available.
2.
Magalhaes M, Dominguez-Martin E, Jorge J, Goncalves A, Massenzio F, Spigarelli R, et al.
J Ethnopharmacol
. 2024 Aug;
335:118689.
PMID: 39128799
Ethnopharmacological Relevance: Glioblastoma (GB) is the most aggressive and prevalent glioma within the central nervous system. Despite considerable efforts, GB continues to exhibit a dismal 5-year survival rate (∼6%). This...
3.
Balboni N, Babini G, Poeta E, Protti M, Mercolini L, Magnifico M, et al.
Cell Mol Biol Lett
. 2024 Mar;
29(1):44.
PMID: 38553684
Aspartate-glutamate carrier isoform 1 (AGC1) is a carrier responsible for the export of mitochondrial aspartate in exchange for cytosolic glutamate and is part of the malate-aspartate shuttle, essential for the...
4.
Albertini C, Petralla S, Massenzio F, Monti B, Rizzardi N, Bergamini C, et al.
Arch Pharm (Weinheim)
. 2024 Feb;
357(6):e2300525.
PMID: 38412454
Lewy body dementia (LBD) represents the second most common neurodegenerative dementia but is a quite underexplored therapeutic area. Nepflamapimod (1) is a brain-penetrant selective inhibitor of the alpha isoform of...
5.
Fazzina M, Bergonzoni M, Massenzio F, Monti B, Frabetti F, Casadei R
Sci Rep
. 2024 Jan;
14(1):2431.
PMID: 38287074
Microglia represent the primary immune defense system within the central nervous system and play a role in the inflammatory processes occurring in numerous disorders, such as Parkinson's disease (PD). PD...
6.
Protti M, Cirrincione M, Palano S, Poeta E, Babini G, Magnifico M, et al.
J Pharm Biomed Anal
. 2023 Oct;
236:115757.
PMID: 37801818
The accurate characterisation of metabolic profiles is an important prerequisite to determine the rate and the efficiency of the metabolic pathways taking place in the cells. Changes in the balance...
7.
morphological alterations of TAMs during KCa3.1 inhibition-by using two-photon time-lapse technology
Massenzio F, Cambiaghi M, Marchiotto F, Boriero D, Limatola C, DAlessandro G, et al.
Front Cell Neurosci
. 2023 Jan;
16:1002487.
PMID: 36589283
Tumor associated macrophages (TAMs) are the mostprevalent cells recruited in the tumor microenvironment (TME). Once recruited, TAMs acquire a pro-tumor phenotype characterized by a typical morphology: ameboid in the tumor...
8.
De Chirico F, Poeta E, Babini G, Piccolino I, Monti B, Massenzio F
Front Cell Neurosci
. 2022 Dec;
16:1038721.
PMID: 36523814
Microglia activation and neuroinflammation have been extensively studied in murine models of neurodegenerative diseases; however, to overcome the genetic differences between species, a human cell model of microglia able to...
9.
Albertini C, Salerno A, Atzeni S, Uliassi E, Massenzio F, Maruca A, et al.
ACS Chem Neurosci
. 2022 Jul;
13(15):2252-2260.
PMID: 35868251
Polypharmacology is a new trend in amyotrophic lateral sclerosis (ALS) therapy and an effective way of addressing a multifactorial etiology involving excitotoxicity, mitochondrial dysfunction, oxidative stress, and microglial activation. Inspired...
10.
Poeta E, Petralla S, Babini G, Renzi B, Celauro L, Magnifico M, et al.
Front Cell Neurosci
. 2022 Jan;
15:773709.
PMID: 35095421
Mitochondrial aspartate-glutamate carrier isoform 1 (AGC1) deficiency is an ultra-rare genetic disease characterized by global hypomyelination and brain atrophy, caused by mutations in the gene leading to a reduction in...