Francesca M Notarangelo
Overview
Explore the profile of Francesca M Notarangelo including associated specialties, affiliations and a list of published articles.
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29
Citations
845
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Recent Articles
1.
Schwarcz R, Foo A, Sathyasaikumar K, Notarangelo F
Int J Mol Sci
. 2024 Apr;
25(7).
PMID: 38612489
The gut-brain axis is increasingly understood to play a role in neuropsychiatric disorders. The probiotic bacterium and products of tryptophan degradation, specifically the neuroactive kynurenine pathway (KP) metabolite kynurenic acid...
2.
Daniels E, Eaton W, cihakova D, Talor M, Lemke H, Mo C, et al.
Schizophr Res
. 2023 May;
256:50-51.
PMID: 37150147
No abstract available.
3.
Hare S, Adhikari B, Mo C, Chen S, Wijtenburg S, Seneviratne C, et al.
Neuropsychopharmacology
. 2023 Apr;
48(11):1594-1601.
PMID: 37118058
Cognitive impairments predict poor functional outcomes in people with schizophrenia. These impairments may be causally related to increased levels of kynurenic acid (KYNA), a major metabolic product of tryptophan (TRYP)....
4.
Chung T, Bopp T, Ward C, Notarangelo F, Schwarcz R, Westbrook R, et al.
Aging Cell
. 2023 Apr;
22(7):e13849.
PMID: 37078472
Decline in neuromuscular function with aging is known to be a major determinant of disability and all-cause mortality in late life. Despite the importance of the problem, the neurobiology of...
5.
Sathyasaikumar K, Notarangelo F, Kelly D, Rowland L, Hare S, Chen S, et al.
Pharmaceuticals (Basel)
. 2022 Aug;
15(8).
PMID: 36015151
The pivotal tryptophan (TRP) metabolite kynurenine is converted to several neuroactive compounds, including kynurenic acid (KYNA), which is elevated in the brain and cerebrospinal fluid of people with schizophrenia (SZ)...
6.
Notarangelo F, Schwarcz R
Eur J Neurosci
. 2021 Aug;
54(6):5968-5981.
PMID: 34363411
In rodents, a single injection of lipopolysaccharide (LPS) during gestation causes chemical and functional abnormalities in the offspring. These effects may involve changes in the kynurenine pathway (KP) of tryptophan...
7.
Kelly D, Kane M, Fraser C, Sayer M, Grant-Beurmann S, Liu T, et al.
J Clin Psychopharmacol
. 2021 Feb;
41(2):200-202.
PMID: 33587401
No abstract available.
8.
Notarangelo F, Beggiato S, Schwarcz R
Dev Neurosci
. 2019 May;
41(1-2):102-111.
PMID: 31117076
Several lines of evidence support the hypothesis that abnormally elevated brain levels of kynurenic acid (KYNA), a metabolite of the kynurenine pathway (KP) of tryptophan degradation, play a pathophysiologically significant...
9.
Primiceri E, Chiriaco M, Notarangelo F, Crocamo A, Ardissino D, Cereda M, et al.
Sensors (Basel)
. 2018 Oct;
18(11).
PMID: 30355989
A major trend in biomedical engineering is the development of reliable, self-contained point-of-care (POC) devices for diagnostics and in-field assays. The new generation of such platforms increasingly addresses the clinical...
10.
Beggiato S, Notarangelo F, Sathyasaikumar K, Giorgini F, Schwarcz R
J Psychopharmacol
. 2018 Oct;
32(11):1223-1232.
PMID: 30354938
Background: Several studies suggest a pathophysiologically relevant association between increased brain levels of the neuroinhibitory tryptophan metabolite kynurenic acid and cognitive dysfunctions in people with schizophrenia. Elevated kynurenic acid in...