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Francesca Finetti

Explore the profile of Francesca Finetti including associated specialties, affiliations and a list of published articles. Areas
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Articles 34
Citations 1825
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Recent Articles
1.
Cassioli C, Capitani N, Staton C, Schirra C, Finetti F, Onnis A, et al.
Proc Natl Acad Sci U S A . 2025 Feb; 122(6):e2413866122. PMID: 39903110
Cytotoxic attack particles released by CTLs and NK cells include diverse phospholipid membrane and glycoprotein encapsulated entities that contribute to target cell killing. Supramolecular attack particles (SMAPs) are one type...
2.
Migliore L, Cianfanelli V, Zevolini F, Gesualdo M, Marzuoli L, Patrussi L, et al.
Sci Rep . 2024 Dec; 14(1):31838. PMID: 39738384
The scaffold protein AMBRA1, which participates in the autophagy pathway, also promotes CD4 T cell differentiation to Tregs independent of autophagy through its interactor PP2A. Here we have investigated the...
3.
Boncompagni G, Tatangelo V, Lopresti L, Ulivieri C, Capitani N, Tangredi C, et al.
Cell Death Dis . 2024 Feb; 15(2):144. PMID: 38360867
The tumor microenvironment (TME) plays a central role in the pathogenesis of chronic lymphocytic leukemia (CLL), contributing to disease progression and chemoresistance. Leukemic cells shape the TME into a pro-survival...
4.
Zevolini F, Onnis A, Khazen R, Muller S, Marotta G, Valitutti S, et al.
J Cell Sci . 2023 Dec; 137(5). PMID: 38084966
Elimination of virally infected or tumoral cells is mediated by cytotoxic T cells (CTL). Upon antigen recognition, CTLs assemble a specialized signaling and secretory domain at the interface with their...
5.
Onnis A, Andreano E, Cassioli C, Finetti F, Della Bella C, Staufer O, et al.
J Exp Med . 2022 Nov; 220(2). PMID: 36378226
CTL-mediated killing of virally infected or malignant cells is orchestrated at the immune synapse (IS). We hypothesized that SARS-CoV-2 may target lytic IS assembly to escape elimination. We show that...
6.
Finetti F, Onnis A, Baldari C
Int J Mol Sci . 2022 Oct; 23(20). PMID: 36292997
Initially discovered as the smallest component of the intraflagellar transport (IFT) system, the IFT20 protein has been found to be implicated in several unconventional mechanisms beyond its essential role in...
7.
Cassioli C, Onnis A, Finetti F, Capitani N, Brunetti J, Compeer E, et al.
J Cell Sci . 2021 Aug; 134(16). PMID: 34423835
Components of the intraflagellar transport (IFT) system that regulates the assembly of the primary cilium are co-opted by the non-ciliated T cell to orchestrate polarized endosome recycling and to sustain...
8.
Capitani N, Onnis A, Finetti F, Cassioli C, Plebani A, Brunetti J, et al.
Cell Death Differ . 2021 Jul; 29(1):65-81. PMID: 34294890
Ciliogenesis proteins orchestrate vesicular trafficking pathways that regulate immune synapse (IS) assembly in the non-ciliated T-cells. We hypothesized that ciliogenesis-related genes might be disease candidates for common variable immunodeficiency with...
9.
Finetti F, Cassioli C, Cianfanelli V, Zevolini F, Onnis A, Gesualdo M, et al.
Front Cell Dev Biol . 2021 Apr; 9:634003. PMID: 33829015
Lymphocyte homeostasis, activation and differentiation crucially rely on basal autophagy. The fine-tuning of this process depends on autophagy-related (ATG) proteins and their interaction with the trafficking machinery that orchestrates the...
10.
Klionsky D, Abdel-Aziz A, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, et al.
Autophagy . 2021 Feb; 17(1):1-382. PMID: 33634751
In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our...