Francesca Cianfarani
Overview
Explore the profile of Francesca Cianfarani including associated specialties, affiliations and a list of published articles.
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Articles
26
Citations
1091
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0
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Recent Articles
1.
Wallace E, ODwyer J, Dolan E, Burke L, Wylie R, Bellavia G, et al.
Adv Sci (Weinh)
. 2024 Dec;
12(7):e2401744.
PMID: 39692747
Therapeutic proteins, the fastest growing class of pharmaceuticals, are subject to rapid proteolytic degradation in vivo, rendering them inactive. Sophisticated drug delivery systems that maintain protein stability, prolong therapeutic effects,...
2.
Primerano A, De Domenico E, Cianfarani F, De Luca N, Floriddia G, Teson M, et al.
Br J Dermatol
. 2024 May;
191(4):568-579.
PMID: 38820176
Background: Recessive dystrophic epidermolysis bullosa (RDEB) is a blistering disease caused by mutations in the gene encoding type VII collagen (C7). RDEB is associated with fibrosis, which is responsible for...
3.
Levey R, Tornifoglio B, Stone A, Kerskens C, Robinson S, Coulter F, et al.
Polymers (Basel)
. 2022 Nov;
14(22).
PMID: 36432947
Analysing the composition and organisation of the fibrous capsule formed as a result of the Foreign Body Response (FBR) to medical devices, is imperative for medical device improvement and biocompatibility....
4.
Coulter F, Levey R, Robinson S, Dolan E, Deotti S, Monaghan M, et al.
Adv Healthc Mater
. 2021 Jun;
10(14):e2100229.
PMID: 34165264
Medical devices, such as silicone-based prostheses designed for soft tissue implantation, often induce a suboptimal foreign-body response which results in a hardened avascular fibrotic capsule around the device, often leading...
5.
Baldini E, Testa E, Voellenkle C, De Domenico E, Cianfarani F, Martelli F, et al.
J Dermatol Sci
. 2020 May;
98(3):186-194.
PMID: 32402513
Background: Clinical skin manifestations are common in diabetes; however, molecular mechanisms underlying such defects are largely unknown. Several findings indicate a role for microRNAs (miRNAs) in skin homeostasis. Objective: To...
6.
Duffy G, Robinson S, OConnor R, Wylie R, Mauerhofer C, Bellavia G, et al.
Adv Healthc Mater
. 2020 Apr;
9(11):e2000305.
PMID: 32339411
Regenerative medicine approaches, specifically stem cell technologies, have demonstrated significant potential to treat a diverse array of pathologies. However, such approaches have resulted in a modest clinical benefit, which may...
7.
Fortugno P, Condorelli A, Dellambra E, Guerra L, Cianfarani F, Tinaburri L, et al.
Int J Mol Sci
. 2020 Feb;
21(4).
PMID: 32093196
Variably reduced expression of the basement membrane component laminin-332 (α3aβ3γ2) causes junctional epidermolysis bullosa generalized intermediate (JEB-GI), a skin fragility disorder with an increased susceptibility to squamous cell carcinoma (SCC)...
8.
Cianfarani F, De Domenico E, Nystrom A, Mastroeni S, Abeni D, Baldini E, et al.
Matrix Biol
. 2018 Dec;
81:3-16.
PMID: 30528862
Loss-of-function mutations in the gene encoding type VII collagen underlie recessive dystrophic epidermolysis bullosa (RDEB), a disease characterized by skin and mucosal blistering, impaired wound healing, and diffuse dermal inflammation...
9.
La Manna S, Scognamiglio P, Di Natale C, Leone M, Mercurio F, Malfitano A, et al.
Biochimie
. 2017 May;
138:106-115.
PMID: 28479106
Interleukin-22 (IL-22) belongs to the family of IL-10 cytokines and is involved in a wide number of human diseases, including inflammatory disorders and cancer pathology. The ligand-receptor complex IL-22/IL-22R plays...
10.
Cianfarani F, Zambruno G, Castiglia D, Odorisio T
Am J Pathol
. 2017 May;
187(7):1445-1453.
PMID: 28460207
Individuals with recessive dystrophic epidermolysis bullosa (RDEB), a rare genetic skin disease, carry mutations in the COL7A1 gene that codes for type VII collagen, an extracellular matrix component of the...