Fran M Gengo
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Explore the profile of Fran M Gengo including associated specialties, affiliations and a list of published articles.
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6
Citations
29
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Recent Articles
1.
Mechtler L, Gengo F, Bargnes V
Curr Pain Headache Rep
. 2021 Feb;
25(3):16.
PMID: 33630181
Purpose Of Review: The use of cannabis for the treatment of migraine has become an area of interest with the legalization of medical cannabis in the USA. Understanding the mechanisms...
2.
Westphal E, Rainka M, Amsler M, Aladeen T, Wisniewski C, Bates V, et al.
J Clin Pharmacol
. 2018 May;
58(9):1157-1163.
PMID: 29775206
This study tested the capability of an assay to predict aspirin response and reduce ischemic events, and healthcare costs, and delays to optimal treatment. Patients who needed aspirin in the...
3.
Westphal E, Wisniewski C, Rainka M, Smith N, Bates V, Gengo F
J Clin Pharmacol
. 2018 May;
58(9):1150-1156.
PMID: 29775202
Aspirin remains the standard for stroke prophylaxis. However, as many as 20%-25% of patients may fail to show a full response to aspirin. Ideally, patients who are resistant to aspirin...
4.
Przespolewski E, Westphal E, Rainka M, Smith N, Bates V, Gengo F
J Stroke Cerebrovasc Dis
. 2018 Feb;
27(6):1582-1589.
PMID: 29449127
Background And Goal: Cytochrome P450 (CYP) enzymes are responsible for the conversion of clopidogrel into its active metabolite and the metabolism of proton pump inhibitors (PPIs), which may also inhibit...
5.
Venci J, Rowcliffe M, Wollenberg L, Rainka M, Gengo F
Forensic Sci Med Pathol
. 2012 Aug;
9(1):73-6.
PMID: 22915321
The antiepileptic, carbamazepine, is extensively metabolized via hepatic enzymes in the cytochrome P450 family and is therefore subject to a myriad of drug interactions. Concomitant administration with phenytoin enhances carbamazepine...
6.
Hong Y, Gengo F, Rainka M, Bates V, Mager D
Clin Pharmacokinet
. 2008 Jan;
47(2):129-37.
PMID: 18193919
Objective: The objective of this study was to develop a mechanism-based pharmacodynamic model that characterizes the antiplatelet effects of aspirin (acetylsalicylic acid) and ibuprofen alone and in combination. Methods: Ten...