Florian Weiland
Overview
Explore the profile of Florian Weiland including associated specialties, affiliations and a list of published articles.
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Articles
21
Citations
276
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Recent Articles
1.
Jadav R, Weiland F, Noordermeer S, Carroll T, Gao Y, Wang J, et al.
Mol Cell Proteomics
. 2024 Jun;
23(8):100802.
PMID: 38880245
The ATR kinase protects cells against DNA damage and replication stress and represents a promising anti-cancer drug target. The ATR inhibitors (ATRi) berzosertib and gartisertib are both in clinical trials...
2.
Inesta-Vaquera F, Weiland F, Henderson C, Wolf C
J Cell Mol Med
. 2022 Oct;
26(21):5463-5472.
PMID: 36201626
Age-related diseases account for a high proportion of the total global burden of disease. Despite recent advances in understanding their molecular basis, there is a lack of suitable early biomarkers...
3.
Khanam T, Munoz I, Weiland F, Carroll T, Morgan M, Borsos B, et al.
EMBO J
. 2021 Oct;
40(23):e108271.
PMID: 34605059
Mutations in the gene encoding the CDKL5 kinase are among the most common genetic causes of childhood epilepsy and can also give rise to the severe neurodevelopmental condition CDD (CDKL5...
4.
Enot M, Weiland F, Mittal P, Hoffmann P, Sillero-Mahinay M, Pukala T
J Mass Spectrom
. 2020 Nov;
56(4):e4689.
PMID: 33247490
The present study investigated Rhoeo discolor (L. Her.) Hance for its ability to accumulate Pb, which is of relevance to phytoremediation applications. Based on this analysis, plants were found to...
5.
Weiland F, Lokman N, Klingler-Hoffmann M, Jobling T, Stephens A, Sundfeldt K, et al.
Front Oncol
. 2020 Oct;
10:1767.
PMID: 33102207
Ovarian cancer is the most lethal gynecologic malignancy. Early detection would improve survival, but an effective diagnostic test does not exist. Novel biomarkers for early ovarian cancer diagnosis are therefore...
6.
Munoz I, Morgan M, Peltier J, Weiland F, Gregorczyk M, Brown F, et al.
EMBO J
. 2018 Sep;
37(24).
PMID: 30266825
Mutations in the gene encoding the protein kinase CDKL5 cause a debilitating neurodevelopmental disease termed CDKL5 disorder. The impact of these mutations on CDKL5 function is poorly understood because the...
7.
Chai M, Weiland F, Harvey R, Hoffmann P, Ogunniyi A, Paton J
Sci Rep
. 2017 May;
7(1):2453.
PMID: 28550292
Streptococcus pneumoniae (the pneumococcus) is a human pathogen, accounting for massive global morbidity and mortality. Although asymptomatic colonization of the nasopharynx almost invariably precedes disease, the critical determinants enabling pneumococcal...
8.
Ng Y, Sorvina A, Bader C, Weiland F, Lopez A, Hoffmann P, et al.
J Proteome Res
. 2017 Apr;
16(5):1976-1987.
PMID: 28365999
The evolutionary conserved family of 14-3-3 proteins appears to have a role in integrating numerous intracellular pathways, including signal transduction, intracellular trafficking, and metabolism. However, little is known about how...
9.
Zammit C, Weiland F, Brugger J, Wade B, Winderbaum L, Nies D, et al.
Metallomics
. 2016 Oct;
8(11):1204-1216.
PMID: 27757465
The metal-resistant β-proteobacterium Cupriavidus metallidurans drives gold (Au) biomineralisation and the (trans)formation of Au nuggets largely via unknown biochemical processes, ultimately leading to the reductive precipitation of mobile, toxic Au(i/iii)-complexes....
10.
Weiland F, Arentz G, Klingler-Hoffmann M, McCarthy P, Lokman N, Kaur G, et al.
J Proteome Res
. 2016 Aug;
15(11):4073-4081.
PMID: 27569743
Although acetylation is regarded as a common protein modification, a detailed proteome-wide profile of this post-translational modification may reveal important biological insight regarding differential acetylation of individual proteins. Here we...