Florian C Oberstrass
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Explore the profile of Florian C Oberstrass including associated specialties, affiliations and a list of published articles.
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14
Citations
979
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Recent Articles
1.
Ivanov I, Lebel P, Oberstrass F, Starr C, Parente A, Ierokomos A, et al.
Biophys J
. 2017 Dec;
114(2):278-282.
PMID: 29248150
Single-molecule methods provide direct measurements of macromolecular dynamics, but are limited by the number of degrees of freedom that can be followed at one time. High-resolution rotor bead tracking (RBT)...
2.
Lebel P, Basu A, Oberstrass F, Tretter E, Bryant Z
Nat Methods
. 2014 Feb;
11(4):456-62.
PMID: 24562422
Single-molecule measurements of DNA twist and extension have been used to reveal physical properties of the double helix and to characterize structural dynamics and mechanochemistry in nucleoprotein complexes. However, the...
3.
Oberstrass F, Fernandes L, Lebel P, Bryant Z
Phys Rev Lett
. 2013 May;
110(17):178103.
PMID: 23679785
Changes in global DNA linking number can be accommodated by localized changes in helical structure. We have used single-molecule torque measurements to investigate sequence-specific strand separation and Z-DNA formation. By...
4.
Bryant Z, Oberstrass F, Basu A
Curr Opin Struct Biol
. 2012 Jun;
22(3):304-12.
PMID: 22658779
Over the past two decades, measurements on individual stretched and twisted DNA molecules have helped define the basic elastic properties of the double helix and enabled real-time functional assays of...
5.
Oberstrass F, Fernandes L, Bryant Z
Proc Natl Acad Sci U S A
. 2012 Apr;
109(16):6106-11.
PMID: 22474350
B-DNA becomes unstable under superhelical stress and is able to adopt a wide range of alternative conformations including strand-separated DNA and Z-DNA. Localized sequence-dependent structural transitions are important for the...
6.
Stefl R, Oberstrass F, Hood J, Jourdan M, Zimmermann M, Skrisovska L, et al.
Cell
. 2010 Oct;
143(2):225-37.
PMID: 20946981
Sequence-dependent recognition of dsDNA-binding proteins is well understood, yet sequence-specific recognition of dsRNA by proteins remains largely unknown, despite their importance in RNA maturation pathways. Adenosine deaminases that act on...
7.
Ravindranathan S, Oberstrass F, Allain F
J Mol Biol
. 2009 Dec;
396(3):732-46.
PMID: 20004205
The sterile alpha motif (SAM) domain of VTS1p, a posttranscriptional gene regulator, belongs to a family of SAM domains conserved from yeast to humans. Even though SAM domains were originally...
8.
Oberstrass F, Allain F, Ravindranathan S
J Am Chem Soc
. 2008 Aug;
130(36):12007-20.
PMID: 18698768
RNA recognition by proteins is often accompanied by significant changes in RNA dynamics in addition to conformational changes. However, there are very few studies which characterize the changes in molecular...
9.
Schubert M, Lapouge K, Duss O, Oberstrass F, Jelesarov I, Haas D, et al.
Nat Struct Mol Biol
. 2007 Aug;
14(9):807-13.
PMID: 17704818
Proteins of the RsmA/CsrA family are global translational regulators in many bacterial species. We have determined the solution structure of a complex formed between the RsmE protein, a member of...
10.
Auweter S, Oberstrass F, Allain F
J Mol Biol
. 2007 Jan;
367(1):174-86.
PMID: 17239394
NMR spectroscopy has proven to be a powerful tool for the structure determination of protein/RNA complexes. However, the quality of these structures depends critically on the number of unambiguous intermolecular...