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Florian Brunner

Explore the profile of Florian Brunner including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 86
Citations 1356
Followers 0
Related Specialties
Orthopedics
Neurology
Psychiatry
Top 10 Co-Authors
Lucas M Bachmann
Ulrike Held
Johann Steurer
Mazda Farshad
Oliver Distler
Stefan Dudli
Maria M Wertli
Irina Heggli
Christian W A Pfirrmann
Rudolf Kissling
Published In
BMC Musculoskelet Disord
Eur J Pain
Pain Med
Pain
Spine (Phila Pa 1976)
Affiliations
Soon will be listed here.
Recent Articles
1.
Identification of two biological subgroups of complex regional pain syndrome type 1 by transcriptomic profiling of skin and blood in women
Perez Vertti Valdes M, Jungel A, Bitterli P, Devan J, Rehrauer H, Opitz L, et al.
Mol Med . 2025 Mar; 31(1):94. PMID: 40075262
Background: Patients with Complex Regional Pain Syndrome (CRPS) present prolonged, debilitating pain and functional impairment. Treatments are not disease-modifying due to the poorly understood underlying pathomechanisms. This study aimed to...
2.
The Expression of Toll-like Receptors in Cartilage Endplate Cells: A Role of Toll-like Receptor 2 in Pro-Inflammatory and Pro-Catabolic Gene Expression
Mengis T, Bernhard L, Nuesch A, Heggli I, Herger N, Devan J, et al.
Cells . 2024 Sep; 13(17. PMID: 39272974
Introduction: The vertebral cartilage endplate (CEP), crucial for intervertebral disc health, is prone to degeneration linked to chronic low back pain, disc degeneration, and Modic changes (MC). While it is...
3.
Proteomic analysis of serum in a population-based cohort did not reveal a biomarker for Modic changes
Schulze F, Maatta J, Grad S, Heggli I, Brunner F, Farshad M, et al.
JOR Spine . 2024 Jul; 7(3):e1337. PMID: 39015135
Introduction: Modic changes (MC) are bone marrow lesions of vertebral bones, which can be detected with magnetic resonance imaging (MRI) adjacent to degenerated intervertebral discs. Defined by their appearance on...
4.
Intervertebral disc microbiome in Modic changes: Lack of result replication underscores the need for a consensus in low-biomass microbiome analysis
Mengis T, Zajac N, Bernhard L, Heggli I, Herger N, Devan J, et al.
JOR Spine . 2024 Apr; 7(2):e1330. PMID: 38585427
Introduction: The emerging field of the disc microbiome challenges traditional views of disc sterility, which opens new avenues for novel clinical insights. However, the lack of methodological consensus in disc...
5.
Effect of an interdisciplinary inpatient program for patients with complex regional pain syndrome in reducing disease activity-a single-center prospective cohort study
Schneider S, Wertli M, Henzi A, Hebeisen M, Brunner F
Pain Med . 2024 Mar; 25(7):459-467. PMID: 38530793
Objective: The aim of this study was to evaluate the benefit of inpatient treatment in reducing disease activity in patients with complex regional pain syndrome (CRPS) who have exhausted outpatient...
6.
Contact-Heat Evoked Potentials: Insights into Pain Processing in CRPS Type I
Allmendinger F, Scheuren P, De Schoenmacker I, Brunner F, Rosner J, Curt A, et al.
J Pain Res . 2024 Mar; 17:989-1003. PMID: 38505501
Purpose: The pathophysiological mechanisms underlying the development of chronic pain in complex regional pain syndrome (CRPS) are diverse and involve both peripheral and central changes in pain processing, such as...
7.
Impacts of priming on distinct immunosuppressive mechanisms of mesenchymal stromal cells under translationally relevant conditions
Herger N, Heggli I, Mengis T, Devan J, Arpesella L, Brunner F, et al.
Stem Cell Res Ther . 2024 Mar; 15(1):65. PMID: 38443999
Background: The multimodal properties of mesenchymal stromal cells (MSCs), particularly their ability to modulate immune responses is of high interest in translational research. Pro-inflammatory, hypoxic, and 3D culture priming are...
8.
Morphological and Quantitative Parametric MRI Follow-up of Cartilage Changes Before and After Intra-articular Injection Therapy in Patients With Mild to Moderate Knee Osteoarthritis: A Randomized, Placebo-Controlled Trial
Tschopp M, Pfirrmann C, Brunner F, Fucentese S, Galley J, Stern C, et al.
Invest Radiol . 2024 Feb; 59(9):646-655. PMID: 38421679
Background: Intra-articular injections are routinely used for conservative treatment of knee osteoarthritis (OA). The detailed comparative therapeutic effects of these injections on cartilage tissue are still unclear. Objective: The aim...
9.
An international study to explore the feasibility of collecting standardised outcome data for Complex Regional Pain Syndrome: recommendations for an international clinical research registry
Grieve S, Brunner F, Cabral D, Connett R, Hirata H, Iwasaki N, et al.
Br J Pain . 2023 Dec; 17(5):468-478. PMID: 38107759
Introduction: Complex Regional Pain Syndrome (CRPS) is a persistent pain condition with low prevalence. Multi-centre collaborative research is needed to attain sufficient sample sizes for meaningful studies. This international observational...
10.
Sensory phenotypes in complex regional pain syndrome and chronic low back pain-indication of common underlying pathomechanisms
De Schoenmacker I, Sirucek L, Scheuren P, Lutolf R, Gorrell L, Brunner F, et al.
Pain Rep . 2023 Nov; 8(6):e1110. PMID: 38027464
Introduction: First-line pain treatment is unsatisfactory in more than 50% of chronic pain patients, likely because of the heterogeneity of mechanisms underlying pain chronification. Objectives: This cross-sectional study aimed to...