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Florence Hervatin

Explore the profile of Florence Hervatin including associated specialties, affiliations and a list of published articles. Areas
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Articles 9
Citations 160
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Recent Articles
1.
Beurlet S, Omidvar N, Gorombei P, Krief P, Le Pogam C, Setterblad N, et al.
Blood . 2013 Aug; 122(16):2864-76. PMID: 23943652
Myelodysplastic syndrome (MDS) transforms into an acute myelogenous leukemia (AML) with associated increased bone marrow (BM) blast infiltration. Using a transgenic mouse model, MRP8[NRASD12/hBCL-2], in which the NRAS:BCL-2 complex at...
2.
Le Pogam C, Krief P, Beurlet S, Soulie A, Balitrand N, Cassinat B, et al.
Leuk Res . 2012 Nov; 37(3):312-9. PMID: 23153525
We have previously demonstrated that two prognostic features of myelodysplastic syndromes (MDS) and acute myelogenous leukemia (AML), mutant NRAS and over-expressing BCL-2, cooperate physically and functionally in vivo. Screening of...
3.
Sarda-Mantel L, Alsac J, Boisgard R, Hervatin F, Montravers F, Tavitian B, et al.
J Vasc Surg . 2012 Jun; 56(3):765-73. PMID: 22726755
Objective: Abdominal aortic aneurysm (AAA) is a frequent form of atherothrombotic disease, whose natural history is to enlarge and rupture. Indicators other than AAA diameter would be useful for preventive...
4.
Muzard J, Sarda-Mantel L, Loyau S, Meulemans A, Louedec L, Bantsimba-Malanda C, et al.
PLoS One . 2009 May; 4(5):e5585. PMID: 19440310
Background: Fibrosis, which is characterized by the pathological accumulation of collagen, is recognized as an important feature of many chronic diseases, and as such, constitutes an enormous health burden. We...
5.
Rouzet F, Dominguez Hernandez M, Hervatin F, Sarda-Mantel L, Lefort A, Duval X, et al.
Circulation . 2008 Jan; 117(6):781-9. PMID: 18227388
Background: The pathophysiology of infective endocarditis involves a pathogen/host tissue interaction, leading to formation of infected thrombotic vegetations. Annexin V is a ligand of phosphatidylserines exposed by activated platelets and...
6.
Sarda-Mantel L, Hervatin F, Michel J, Louedec L, Martet G, Rouzet F, et al.
Eur J Nucl Med Mol Imaging . 2007 Sep; 35(1):158-65. PMID: 17805532
Objectives: Phosphatidylserin exposure on cell surfaces occurs early during apoptosis and is detected in vivo by using (99m)Tc-annexin-V (ANX). Cardiomyocyte membrane disruption is detected in vivo by using (111)In-antimyosin-antibodies (AM)....
7.
Sarda-Mantel L, Saleh-Mghir A, Welling M, Meulemans A, Vrigneaud J, Raguin O, et al.
Eur J Nucl Med Mol Imaging . 2007 Mar; 34(8):1302-9. PMID: 17334764
Purpose: (99m)Tc-UBI 29-41 (UBI), an antimicrobial peptide, specifically targets bacteria. We tested the ability of UBI to discriminate between infected and uninfected prosthetic joints using a rabbit model previously validated....
8.
Sarda-Mantel L, Coutard M, Rouzet F, Raguin O, Vrigneaud J, Hervatin F, et al.
Arterioscler Thromb Vasc Biol . 2006 Jul; 26(9):2153-9. PMID: 16857952
Background: The mural thrombus of abdominal aortic aneurysms (AAA) is involved in aneurysm progression via several interdependent biological processes including platelet activation. 99mTc-annexin V (ANX) is a scintigraphic tracer that...
9.
Sarda-Mantel L, Michel J, Rouzet F, Martet G, Louedec L, Vanderheyden J, et al.
Eur J Nucl Med Mol Imaging . 2005 Nov; 33(3):239-45. PMID: 16283183
Purpose: (99m)Tc-annexin V (ANX) allows scintigraphic detection of apoptotic cells via specific binding to exposed phosphatidylserine. In myocardial infarction, apoptosis of myocytes is variable and depends especially on the presence...